CD44 Antikörper

Produktnummer ABIN8063653

Dieser Maus Monoklonal Antikörper detektiert spezifisch CD44 in FACS. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für CD44 Antikörper (ABIN8063653)

Target: CD44

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD44 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS)

Klon: P2A1

Produktdetails anti-CD44 Antikörper

Verwendungszweck: Purified Anti-Human CD44 Antibody[P2A1]

Isotyp: IgG2a, kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: ≥ 1 mg/mL

Buffer: Phosphate buffered solution, pH 7.2, containing 0.05 % proclin 300.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: avoid freeze / thaw cycles.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.

Haltbarkeit: 12 months

Details zu CD44

Target: CD44

Andere Bezeichnung: CD44

Hintergrund: CDW,MIC,CSPG,Phagocytic glycoprotein,MDU,Pgp,CDW44,CSPG8,ECMR-III,HCELL,HUTCH-I,IN,LHR,MC56,MDU2,MDU3,MIC4,Pgp1,CD44,CD44 antigen,Epican,PGP-1,PGP-I,Phagocytic glycoprotein 1,Phagocytic glycoprotein I,H-CAM,CD44v, Pgp-1, EMCR III, CD44s,BA-1,CD 44,CD44 Molecule,CD44 Molecule (Indian blood group),CD44v9,Cell surface glycoprotein CD44,chondroitin sulfate proteoglycan 8,Extracellular matrix receptor III,GP90 lymphocyte homing/adhesion receptor,hematopoietic cell E- and L-selectin ligand,Heparan sulfate proteoglycan,Hermes antigen,homing function and Indian blood group system,HSA,HUTCH1,Hyaluronate receptor,INLU-related p80 Glycoprotein,MGC10468,MUTCH1,Soluble CD44,The protein encoded by this gene is a cell-surface glycoprotein involved in cell-cell interactions, cell adhesion and migration. It is a receptor for hyaluronic acid (HA) and can also interact with other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs). This protein participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis. Transcripts for this gene undergo complex alternative splicing that results in many functionally distinct isoforms, however, the full length nature of some of these variants has not been determined. Alternative splicing is the basis for the structural and functional diversity of this protein, and may be related to tumor metastasis.

UniProt: P16070

Pathways: Glycosaminoglycan Metabolic Process, Autophagie, Negative Regulation of intrinsic apoptotic Signaling