TCF4 Antikörper (AA 365-671)

Produktnummer ABIN7660963

Dieses Maus Monoklonal-Antikörper erkennt spezifisch TCF4 in WB. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für TCF4 Antikörper (AA 365-671) (ABIN7660963)

Target: TCF4 (Transcription Factor 4 (TCF4))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser TCF4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: TCF4-1705

Produktdetails anti-TCF4 Antikörper

Bindungsspezifität: AA 365-671

Verwendungszweck: TCF4 (Transcription Factor 4)(TCF4/1705)

Produktmerkmale: This antibody recognizes a protein of 71 kDa, identified as Transcription Factor 4 (TCF4). It is a basic helix-loop-helix transcription factor. The protein recognizes an Ephrussi-box (E-box) binding site (CANNTG) - a motif first identified in immunoglobulin enhancers. This gene is broadly expressed, and may play an important role in nervous system development. Defects in this gene are a cause of Pitt-Hopkins syndrome. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Immunogen: Recombinant human TCF4 protein fragment (around aa 365-671)

Isotyp: IgG2a, kappa

Anwendungsinformationen

Applikationshinweise: ELISA: Use Ab at 2-4 μg/mL for coating, Order Ab without BSA, Western blot 1-2 μg/mL, Optimal dilution for a specific application should be determined.. Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody

Kommentare:

Positive Control: HeLa or HepG2 cells. Bladder

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS, no BSA, no azide

Konservierungsmittel: Without preservative

Lagerung: -20 °C

Informationen zur Lagerung:

Stable at room temperature or 37°C for 7 days.

Store at -20 °C. Protect fluorescent conjugates from light

Haltbarkeit: 24 months

Details zu TCF4

Target: TCF4 (Transcription Factor 4 (TCF4))

Andere Bezeichnung: TCF4

Hintergrund:

Synonyms: bHLHb19, Class B basic helix-loop-helix protein 19, Immunoglobulin transcription factor 2, ITF-2, PTHS, SEF2, SL3-3 enhancer factor 2, TCF4, Transcription factor 4

Gene Symbol: TCF4

Molekulargewicht: 71 kDa

Gen-ID: 6925

UniProt: P15884

Pathways: WNT Signalweg, Positive Regulation of Peptide Hormone Secretion, Peptide Hormone Metabolism, Regulation of Hormone Metabolic Process, Carbohydrate Homeostasis, Stem Cell Maintenance, Protein targeting to Nucleus