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TCL1A Antikörper (AA 2-109) (CF®740)

Dieses Maus Monoklonal-Antikörper erkennt spezifisch TCL1A in WB, IHC und IHC (fp). Er zeigt eine Reaktivität gegenüber Human.
Produktnummer ABIN7660567

Kurzübersicht für TCL1A Antikörper (AA 2-109) (CF®740) (ABIN7660567)

Target

Alle TCL1A Antikörper anzeigen
TCL1A (T-Cell Leukemia/lymphoma 1A (TCL1A))

Reaktivität

  • 77
  • 3
  • 1
Human

Wirt

  • 44
  • 34
  • 1
Maus

Klonalität

  • 45
  • 34
Monoklonal

Konjugat

  • 39
  • 5
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser TCL1A Antikörper ist konjugiert mit CF®740

Applikation

  • 45
  • 31
  • 29
  • 16
  • 10
  • 10
  • 9
  • 6
  • 3
  • 3
  • 2
  • 2
Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Klon

TCL1-2079
  • Bindungsspezifität

    • 35
    • 12
    • 6
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 2-109

    Verwendungszweck

    TCL1 (T-Cell Marker)(TCL1/2079), CF740 conjugate

    Produktmerkmale

    T-cell leukemia/Lymphoma Protein 1A (TCL-1A), also known as p14TCL1 is a product of the TCL1 gene that is involved in T-cell prolymphocytic leukemia (TPLL). T-PLL is a rare form of mature T-cell leukemia, which is consistently associated with chromosomal rearrangements characterized by the juxtaposition of the TCRA locus on chromosome 14q11 and the TCL1A gene on 14q32. 13. TCL1 is overexpressed in Burkitt lymphoma, the majority of AIDS-related non-Hodgkin lymphoma-designated immunoblastic plasmacytoid lymphoma, lymphoblastic lymphoma, chronic lymphocytic leukemia, mantle cell lymphoma, follicular lymphoma, diffuse large B-cell lymphoma, and primary cutaneous B-cell lymphoma. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

    Immunogen

    Recombinant fragment (around aa 2-109) of human TCL1 protein

    Isotyp

    IgG2a, kappa
  • Applikationshinweise

    Optimal working dilution should be determined by the investigator.

    Kommentare

    Positive Control: Ramos or Raji cells. Tonsil or T-cell Lymphoma.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    0.1 mg/mL

    Buffer

    PBS, 0.1 % rBSA, 0.05 % azide

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handhabung

    Protect from light

    Lagerung

    4 °C

    Informationen zur Lagerung

    Stable at room temperature or 37°C for 7 days.

    Protect from light

    Store at 2 to 8°C. Protect fluorescent conjugates from light

    Haltbarkeit

    24 months
  • Target

    TCL1A (T-Cell Leukemia/lymphoma 1A (TCL1A))

    Andere Bezeichnung

    TCL1

    Hintergrund

    Synonyms: TCL1A, Lymphoma/leukemia, T-cell, Oncogene TCL1, P14 TCL1, T cell leukemia 1, T cell lymphoma 1, T cell lymphoma 1A, T-cell leukemia/lymphoma 1A, TCL1, TCL1A

    Gene Symbol: TCL1A

    Molekulargewicht

    14 kDa

    Gen-ID

    10232

    UniProt

    P56279

    Pathways

    Stem Cell Maintenance
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