PODXL Antikörper (AA 310-447) (Biotin)

Produktnummer ABIN7658750

Der Maus Monoklonal Anti-PODXL-Antikörper wurde für IHC und IHC (fp) validiert. Er ist geeignet, PODXL in Proben von Human zu detektieren.

Kurzübersicht für PODXL Antikörper (AA 310-447) (Biotin) (ABIN7658750)

Target: PODXL (Podocalyxin-Like (PODXL))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser PODXL Antikörper ist konjugiert mit Biotin

Applikation: Immunohistochemistry (IHC), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Klon: PODXL-2184

Produktdetails anti-PODXL Antikörper (Biotin)

Bindungsspezifität: AA 310-447

Verwendungszweck: Podocalyxin (PODXL) (Hematopoietic Stem Cell Marker)(PODXL/2184), Biotin conjugate

Produktmerkmale: Podocalyxin is a member of the CD34 transmembrane sialomucin family. It is over-expressed on the podocyte foot projections and plays essential roles in kidney development and homeostasis, blood filtration and urine formation. It is also expressed on vascular endothelia, hematopoietic progenitors and a subset of neurons. Overexpression of podocalyxin may be linked to more aggressive tumor behavior. Podocalyxin antibody can identify podocytes in the urine (podocyturia) that may indicate glomerular disease, pre-eclampsia, and other kidney pathology. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Immunogen: Recombinant fragment of human Podocalyxin (around aa 310-447)

Isotyp: IgG1, kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

Positive Control: HeLa, Raji, Jurkat cells, Angiosarcoma, Breast, Prostate, Liver, Pancreatic, Kidney

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.1 mg/mL

Buffer: PBS, 0.1 % BSA, 0.05 % azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung:

Stable at room temperature or 37°C for 7 days.

Store at 2 to 8°C. Protect fluorescent conjugates from light

Haltbarkeit: 24 months

Details zu PODXL

Target: PODXL (Podocalyxin-Like (PODXL))

Andere Bezeichnung: Podocalyxin

Hintergrund:

Synonyms: PODXL, PDXL, GCTM-2, Gp200, PCLP1, Pcx, Podocalyxin-like protein 1

Gene Symbol: PODXL

Tissue Expression: Kidney

Molekulargewicht: 165-170 kDa

Gen-ID: 5420

UniProt: O00592

Pathways: Tube Formation