BMI1 Antikörper (AA 142-326)

Produktnummer ABIN7650105

Dieses Anti-BMI1-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von BMI1 in WB, IHC und IHC (fp). Geeignet für Human.

Kurzübersicht für BMI1 Antikörper (AA 142-326) (ABIN7650105)

Target: BMI1 (BMI1 Polycomb Ring Finger Oncogene (BMI1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser BMI1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Klon: BMI1-2689

Produktdetails anti-BMI1 Antikörper

Bindungsspezifität: AA 142-326

Verwendungszweck: BMI1 (Oncogene and Stem Cell Marker)(BMI1/2689)

Produktmerkmale: The B cell-specific moloney murine leukemia virus integration site 1 (Bmi-1) is a transcriptional receptor of the polycomb gene family involved in several cellular processes including cell-cycle regulation, apoptosis, and maintenance of adult and neoplastic stem cells by providing self-renewal capacity. Further, Bmi-1 expression has been associated with malignant transformation, tumor progression, metastatic disease, and poor prognosis in human malignancies. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Immunogen: Recombinant fragment of human BMI1 protein (around aa 142-326)

Isotyp: IgG1, kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

Positive Control: 293T, NIH3T3, HeLa or Jurkat cells. Colon Carcinoma.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS, no BSA, no azide

Konservierungsmittel: Without preservative

Lagerung: -20 °C

Informationen zur Lagerung:

Stable at room temperature or 37°C for 7 days.

Store at -20 °C. Protect fluorescent conjugates from light

Haltbarkeit: 24 months

Details zu BMI1

Target: BMI1 (BMI1 Polycomb Ring Finger Oncogene (BMI1))

Andere Bezeichnung: BMI1

Hintergrund:

Synonyms: BMI1, Polycomb complex protein BMI1, B lymphoma Mo MLV insertion region 1 homolog, BMI1 polycomb ring finger oncogene, Polycomb group ring finger 4, RING finger protein 51

Gene Symbol: BMI1

Molekulargewicht: ~41 kDa

Gen-ID: 648

UniProt: P35226

Pathways: Zellzyklus, Autophagie