AMPD3 Antikörper (CF®740)

Produktnummer ABIN7649180

Der Maus Monoklonal Anti-AMPD3-Antikörper wurde für IHC und IHC (fp) validiert. Er ist geeignet, AMPD3 in Proben von Human zu detektieren.

Kurzübersicht für AMPD3 Antikörper (CF®740) (ABIN7649180)

Target: AMPD3 (Adenosine Monophosphate Deaminase 3 (AMPD3))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser AMPD3 Antikörper ist konjugiert mit CF®740

Applikation: Immunohistochemistry (IHC), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Klon: AMPD3-901

Produktdetails anti-AMPD3 Antikörper (CF®740)

Verwendungszweck: Adenosine Monophosphate Deaminase 3 (AMPD3)(AMPD3/901), CF740 conjugate

Produktmerkmale: Adenosine Monophosphate Deaminase, isoform E (AMPD3) is a highly regulated enzyme that catalyzes the hydrolytic deamination of adenosine monophosphate to inosine monophosphate, a branch point in the adenylate catabolic pathway. AMPD3 gene encodes the erythrocyte (E) isoforms, whereas other family members encode isoforms that predominate in muscle (M) and liver (L) cells. It has 767 amino acids, a MW of ~ 90 kDa, and is assigned an EC 3.5.4.6. This MAb shows reactivity with cells of the erythroid lineage at all stages of maturation in the peripheral blood, bone marrow, and fetal liver. Non-erythroid lineages are negative by flow cytometry. This MAb is useful in the diagnosis of erythroleukemia, identification of bone marrow erythroid precursors, gating erythroid nucleated precursor cells from malignant cells in bone marrow specimens.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Immunogen: Recombinant full-length human AMDP3 protein

Isotyp: IgG2b, kappa

Anwendungsinformationen

Applikationshinweise: Immunohistology formalin-fixed 2-4 μg/mL. Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes. Immunocytochemistry 1-2.0 μg/mL. Immunofluorescence 0.5-1 μg/mL. Flow Cytometry 1-2 μg/million cells in 0.1 mL. Optimal dilution for a specific application should be determined by user

Kommentare:

Positive Control: RBC. Fetal liver, Spleen or Placenta

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.1 mg/mL

Buffer: PBS, 0.1 % rBSA, 0.05 % azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Protect from light

Lagerung: 4 °C

Informationen zur Lagerung:

Stable at room temperature or 37°C for 7 days.

Protect from light

Store at 2 to 8°C. Protect fluorescent conjugates from light

Haltbarkeit: 24 months

Details zu AMPD3

Target: AMPD3 (Adenosine Monophosphate Deaminase 3 (AMPD3))

Andere Bezeichnung: Adenosine Monophosphate Deaminase-3

Hintergrund:

Synonyms: AMPD3, Erythrocyte AMP Deaminase, AMP Deaminase 3

Gene Symbol: AMPD3

Tissue Expression: Red blood cells

Molekulargewicht: 90 kDa

Gen-ID: 272

UniProt: Q01432