AMPD3 Antikörper

Produktnummer ABIN6939530

Dieser Maus Monoklonal Antikörper detektiert spezifisch AMPD3 in IHC. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für AMPD3 Antikörper (ABIN6939530)

Target: AMPD3 (Adenosine Monophosphate Deaminase 3 (AMPD3))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser AMPD3 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC)

Klon: AMPD3-901

Produktdetails anti-AMPD3 Antikörper

Verwendungszweck: AMP Deaminase, Isoform E (AMPD3) (Erythroid Marker) Antibody

Spezifität: It recognizes a protein of ~90 kDa, which is identified as Adenosine Monophosphate Deaminase, isoform E (AMPD3). It has 767 amino acids and is assigned an EC 3.5.4.6. It is a highly regulated enzyme that catalyzes the hydrolytic deamination of adenosine monophosphate to inosine monophosphate, a branch point in the adenylate catabolic pathway. AMPD3 gene encodes the erythrocyte (E) isoforms, whereas other family members encode isoforms that predominate in muscle (M) and liver (L) cells. This MAb shows reactivity with cells of the erythroid lineage at all stages of maturation in the peripheral blood, bone marrow, and fetal liver. Non-erythroid lineages are negative by flow cytometry. This MAb is useful in the diagnosis of erythroleukemia, identification of bone marrow erythroid precursors, gating erythroid nucleated precursor cells from malignant cells in bone marrow specimens.

Aufreinigung: 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant full-length human AMDP3 protein

Isotyp: IgG2b, kappa

Anwendungsinformationen

Applikationshinweise:

Positive Control: RBC. Fetal liver, Spleen or Placenta.

Known Application: Immunohistochemistry (Formalin-fixed) (2-4 μg/mL for 30 minutes at RT) (Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Haltbarkeit: 24 months

Details zu AMPD3

Target: AMPD3 (Adenosine Monophosphate Deaminase 3 (AMPD3))

Andere Bezeichnung: AMPD3

Hintergrund:

Adenosine monophosphate deaminase (isoform E), AMP aminohydrolase, AMP deaminase 3, AMP deaminase isoform E, Ampd3, Erythrocyte AMP deaminase, Erythrocyte specific AMP deaminase, Erythrocyte specific protein, Erythrocyte type AMP deaminase, Myoadenylate deaminase

RBC. Fetal liver, Spleen or Placenta.

Molekulargewicht: ~90kDa

Gen-ID: 272, 501890

UniProt: Q01432