TARDBP Antikörper (AA 21-120) (Biotin)
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- Target Alle TARDBP Antikörper anzeigen
- TARDBP (TAR DNA Binding Protein (TARDBP))
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Bindungsspezifität
- AA 21-120
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Reaktivität
- Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser TARDBP Antikörper ist konjugiert mit Biotin
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Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Kreuzreaktivität
- Ratte
- Homologie
- Human,Mouse,Cow,Chicken,Rabbit
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human TDP-43
- Isotyp
- IgG
- Top Product
- Discover our top product TARDBP Primärantikörper
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- Applikationshinweise
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WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C for 12 months.
- Haltbarkeit
- 12 months
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- Target
- TARDBP (TAR DNA Binding Protein (TARDBP))
- Andere Bezeichnung
- TARDBP (TARDBP Produkte)
- Synonyme
- TARDBP antikoerper, TDP43 antikoerper, DKFZp459I2127 antikoerper, tardbp antikoerper, ALS10 antikoerper, TDP-43 antikoerper, 1190002A23Rik antikoerper, C85084 antikoerper, Tdp43 antikoerper, wu:fb77f02 antikoerper, wu:fc52g10 antikoerper, TAR DNA binding protein antikoerper, Tardbp protein antikoerper, TAR DNA binding protein L homeolog antikoerper, TAR DNA-binding protein 43-like antikoerper, TARDBP antikoerper, tardbp antikoerper, tardbp.L antikoerper, Tardbp antikoerper, LOC100621383 antikoerper
- Hintergrund
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Synonyms: ALS10, TDP-43, TAR DNA-binding protein 43, TARDBP, TDP43
Background: DNA and RNA-binding protein which regulates transcription and splicing. Involved in the regulation of CFTR splicing. It promotes CFTR exon 9 skipping by binding to the UG repeated motifs in the polymorphic region near the 3'-splice site of this exon. The resulting aberrant splicing is associated with pathological features typical of cystic fibrosis. May also be involved in microRNA biogenesis, apoptosis and cell division. Can repress HIV-1 transcription by binding to the HIV-1 long terminal repeat. Stabilizes the low molecular weight neurofilament (NFL) mRNA through a direct interaction with the 3' UTR.
- Gen-ID
- 23435
- UniProt
- Q13148
- Pathways
- Positive Regulation of Peptide Hormone Secretion
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