VEGFR2/CD309 Antikörper (Biotin)

Produktnummer ABIN7608406

Dieses Kaninchen Monoklonal-Antikörper erkennt spezifisch VEGFR2/CD309 in ELISA und FACS. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für VEGFR2/CD309 Antikörper (Biotin) (ABIN7608406)

Target: VEGFR2/CD309 (VEGFR2) (VEGF Receptor 2 (VEGFR2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser VEGFR2/CD309 Antikörper ist konjugiert mit Biotin

Applikation: ELISA, Flow Cytometry (FACS)

Klon: DM185

Produktdetails anti-VEGFR2/CD309 Antikörper (Biotin)

Verwendungszweck: Biotinylated Anti-VEGFR2 antibody(DM185), Rabbit mAb

Aufreinigung: Purified from cell culture supernatant by affinity chromatography

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA 1:5000-10000, Flow Cyt 1:100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Haltbarkeit: 12 months

Details zu VEGFR2/CD309

Target: VEGFR2/CD309 (VEGFR2) (VEGF Receptor 2 (VEGFR2))

Andere Bezeichnung: VEGFR2

Hintergrund: Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, T-cell protein tyrosine phosphatase, etc.. Mutations of this gene are implicated in infantile capillary hemangiomas.

UniProt: P35968

Pathways: RTK Signalweg, Glycosaminoglycan Metabolic Process, Signaling Events mediated by VEGFR1 and VEGFR2, Growth Factor Binding, Regulation of long-term Neuronal Synaptic Plasticity, VEGF Signaling