Rekombinanter IL5RA Antikörper (Biotin)

Produktnummer ABIN7851663

Dieser Human Chimeric Antikörper detektiert spezifisch IL5RA in FACS. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für Rekombinanter IL5RA Antikörper (Biotin) (ABIN7851663)

Target: IL5RA (Interleukin 5 Receptor, alpha (IL5RA))

Antikörpertyp: Recombinant Antibody

Fragment: Fc fragment

Reaktivität: Human

Wirt: Human, Kaninchen

Klonalität: Chimeric

Konjugat: Dieser IL5RA Antikörper ist konjugiert mit Biotin

Applikation: Flow Cytometry (FACS)

Klon: DMC393

Produktdetails anti-IL5RA Antikörper (Biotin)

Verwendungszweck: Biotinylated Anti-IL5RA antibody(DMC393), IgG1 Chimeric mAb

Aufreinigung: Purified from cell culture supernatant by affinity chromatography

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Flow Cyt 1:100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Please see Certificate of Analysis for specific instructions of reconstitution.

Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Haltbarkeit: 12 months

Details zu IL5RA

Target: IL5RA (Interleukin 5 Receptor, alpha (IL5RA))

Andere Bezeichnung: IL5RA

Hintergrund: The protein encoded by this gene is an interleukin 5 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2:GM-CSF), and interleukin 5 (IL5). The binding of this protein to IL5 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL5. This protein has been found to interact with syndecan binding protein (syntenin), which is required for IL5 mediated activation of the transcription factor SOX4. Several alternatively spliced transcript variants encoding four distinct isoforms have been reported.

UniProt: Q01344

Pathways: JAK-STAT Signalweg