HBEGF Antikörper (Biotin)
Kurzübersicht für HBEGF Antikörper (Biotin) (ABIN7608244)
Target
Alle HBEGF Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
-
-
Verwendungszweck
- Biotinylated Anti-HBEGF antibody(DMC500), IgG1 Chimeric mAb
-
Aufreinigung
- Purified from cell culture supernatant by affinity chromatography
-
Isotyp
- IgG1
-
-
-
-
Applikationshinweise
- Flow Cyt 1:100
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Lyophilized
-
Buffer
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
-
Lagerung
- -20 °C,-80 °C
-
Informationen zur Lagerung
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
-
Haltbarkeit
- 12 months
-
-
- HBEGF (Heparin-Binding EGF-Like Growth Factor (HBEGF))
-
Andere Bezeichnung
- HBEGF
-
Hintergrund
- Growth factor that mediates its effects via EGFR, ERBB2 and ERBB4. Required for normal cardiac valve formation and normal heart function. Promotes smooth muscle cell proliferation. May be involved in macrophage-mediated cellular proliferation. It is mitogenic for fibroblasts, but not endothelial cells. It is able to bind EGF receptor:EGFR with higher affinity than EGF itself and is a far more potent mitogen for smooth muscle cells than EGF. Also acts as a diphtheria toxin receptor.[UniProtKB:Swiss-Prot Function]
-
UniProt
- Q99075
-
Pathways
- RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung
Target
-