PD-1 Antikörper (Biotin)

Produktnummer ABIN7608071

Der Kaninchen Monoklonal Anti-PD-1-Antikörper wurde für ELISA validiert. Er ist geeignet, PD-1 in Proben von Hund zu detektieren.

Kurzübersicht für PD-1 Antikörper (Biotin) (ABIN7608071)

Target: PD-1 (PDCD1) (Programmed Cell Death 1 (PDCD1))

Reaktivität: Hund

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser PD-1 Antikörper ist konjugiert mit Biotin

Applikation: ELISA

Klon: 4-00E-01

Produktdetails anti-PD-1 Antikörper (Biotin)

Verwendungszweck: Biotinylated Anti-Canine PD-1 antibody(4E1), Rabbit mAb

Aufreinigung: Purified from cell culture supernatant by affinity chromatography

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA 1/5000-10000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Haltbarkeit: 12 months

Details zu PD-1

Target: PD-1 (PDCD1) (Programmed Cell Death 1 (PDCD1))

Andere Bezeichnung: PD-1

Hintergrund: Programmed cell death protein 1 (PDCD1) is an immune-inhibitory receptor expressed in activated T cells, it is involved in the regulation of T-cell functions, including those of effector CD8+ T cells. In addition, this protein can also promote the differentiation of CD4+ T cells into T regulatory cells. PDCD1 is expressed in many types of tumors including melanomas, and has demonstrated to play a role in anti-tumor immunity. Moreover, this protein has been shown to be involved in safeguarding against autoimmunity, however, it can also contribute to the inhibition of effective anti-tumor and anti-microbial immunity. [provided by RefSeq, Aug 2020]

NCBI Accession: NP_001301026

Pathways: Cancer Immune Checkpoints