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Cyclin C Antikörper (AA 23-100)

This anti-Cyclin C antibody (ABIN727250) is a Rabbit Polyclonal antibody detecting Cyclin C in WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro). Suitable for Human.
Produktnummer ABIN727250

Kurzübersicht für Cyclin C Antikörper (AA 23-100) (ABIN727250)

Target

Alle Cyclin C (CCNC) Antikörper anzeigen
Cyclin C (CCNC)

Reaktivität

  • 63
  • 31
  • 29
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Human

Wirt

  • 62
  • 1
Kaninchen

Klonalität

  • 63
Polyklonal

Konjugat

  • 25
  • 4
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser Cyclin C Antikörper ist unkonjugiert

Applikation

  • 52
  • 25
  • 25
  • 21
  • 8
  • 7
  • 5
  • 5
  • 4
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • Bindungsspezifität

    • 23
    • 14
    • 7
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 23-100

    Kreuzreaktivität

    Human

    Homologie

    Mouse,Rat

    Aufreinigung

    Purified by Protein A.

    Immunogen

    KLH conjugated synthetic peptide derived from human Cyclin C

    Isotyp

    IgG
  • Applikationshinweise

    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 μg/μL

    Buffer

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    Konservierungsmittel

    ProClin

    Vorsichtsmaßnahmen

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    Haltbarkeit

    12 months
  • Target

    Cyclin C (CCNC)

    Andere Bezeichnung

    Cyclin C

    Hintergrund

    Synonyms: CycC, Cyclin-C, SRB11 homolog, hSRB11, CCNC

    Background: Component of the Mediator complex, a coactivator involved in regulated gene transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. Binds to and activates cyclin-dependent kinase CDK8 that phosphorylates the CTD (C-terminal domain) of the large subunit of RNA polymerase II (RNAp II), which may inhibit the formation of a transcription initiation complex.

    Gen-ID

    892

    UniProt

    P24863

    Pathways

    Zellzyklus, Regulation of Lipid Metabolism by PPARalpha
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