Cyclin C Antikörper (AA 240-283)

Produktnummer ABIN7148838

Produktdetails anti-Cyclin C Antikörper

Target: Cyclin C (CCNC)

Bindungsspezifität: AA 240-283

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Cyclin C Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Kreuzreaktivität: Human, Maus

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Cyclin-C protein (240-283AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu Cyclin C

Target: Cyclin C (CCNC)

Andere Bezeichnung: CCNC (CCNC Produkte)

Synonyme: CG1C_DROME antikoerper, CG7281 antikoerper, CYCC antikoerper, Cln3 antikoerper, Cyc-C antikoerper, DmcycC antikoerper, Dmel\\CG7281 antikoerper, SRB11 antikoerper, cycC antikoerper, cyclinC antikoerper, dTRAP33 antikoerper, fj11d06 antikoerper, wu:fj11d06 antikoerper, zgc:73078 antikoerper, Cyclin-C antikoerper, CycC antikoerper, AI451004 antikoerper, AU020987 antikoerper, CG1C antikoerper, Cyclin C antikoerper, cyclin C antikoerper, cyclin C L homeolog antikoerper, cyclin-C antikoerper, CycC antikoerper, ccnc antikoerper, CCNC antikoerper, Ccnc antikoerper, ccnc.L antikoerper, LOC5577815 antikoerper

Hintergrund:

Background: Component of the Mediator complex, a coactivator involved in regulated gene transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. Binds to and activates cyclin-dependent kinase CDK8 that phosphorylates the CTD (C-terminal domain) of the large subunit of RNA polymerase II (RNAp II), which may inhibit the formation of a transcription initiation complex.

Aliases: ccnc antibody, CCNC_HUMAN antibody, CycC antibody, Cyclin C antibody, Cyclin-C antibody, hSRB11 antibody, OTTHUMP00000016897 antibody, SRB11 homolog antibody

UniProt: P24863

Pathways: Zellzyklus, Regulation of Lipid Metabolism by PPARalpha