Cyclin C Antikörper

Produktnummer ABIN7225722

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch Cyclin C in WB und ELISA. Es zeigt Reaktivität gegenüber Proben von Human, Maus und Ratte.

Kurzübersicht für Cyclin C Antikörper (ABIN7225722)

Target: Cyclin C (CCNC)

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Cyclin C Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-Cyclin C Antikörper

Verwendungszweck: Rabbit Anti-Cyclin C Polyclonal Antibody

Spezifität: Cyclin C Polyclonal Antibody detects endogenous levels of Cyclin C protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human Cyclin C around the non-phosphorylation site of S275

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,ELISA 1:5000,Not yet tested in other applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu Cyclin C

Target: Cyclin C (CCNC)

Andere Bezeichnung: Cyclin C

Hintergrund: CCNC, Cyclin-C, SRB11 homolog, hSRB11The protein encoded by CCNC (cyclin C) is a member of the cyclin family of proteins. The encoded protein interacts with cyclin-dependent kinase 8 and induces the phophorylation of the carboxy-terminal domain of the large subunit of RNA polymerase II. The level of mRNAs for this gene peaks in the G1 phase of the cell cycle. Two transcript variants encoding different isoforms have been found for CCNC.

Molekulargewicht: 33-37kD

Gen-ID: 892

UniProt: P24863

Pathways: Zellzyklus, Regulation of Lipid Metabolism by PPARalpha