EGLN1 Antikörper
Kurzübersicht für EGLN1 Antikörper (ABIN7605935)
Target
Alle EGLN1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
-
-
Verwendungszweck
- Anti-PHD2 / prolyl hydroxylase Monoclonal Antibody
-
Produktmerkmale
- Anti-PHD2 / prolyl hydroxylase Monoclonal Antibody. Tested in WB, IP applications. This antibody reacts with Human.
-
Aufreinigung
- Affinity-chromatography
-
Immunogen
- A synthesized peptide derived from human PHD2 / prolyl hydroxylase Catalyzes the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. Hydroxylates HIF-1 alpha at 'Pro-402' and 'Pro-564', and HIF-2 alpha. Functions as a cellular oxygen sensor and, under normoxic conditions, targets HIF through the hydroxylation for proteasomal degradation via the von Hippel-Lindau ubiquitination complex.
-
Isotyp
- IgG
-
-
-
-
Applikationshinweise
- WB 1:500-2000IP 1:20
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Konzentration
- 0.5 mg/mL
-
Buffer
- Rabbit IgG in stabilizing components, phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Lagerung
- 4 °C,-20 °C
-
Informationen zur Lagerung
- Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
-
Haltbarkeit
- 12 months
-
-
- EGLN1 (Egl-9 Family Hypoxia Inducible Factor 1 (EGLN1))
-
Andere Bezeichnung
- EGLN1
-
Hintergrund
- Egl-9 family hypoxia inducible factor 1
-
Molekulargewicht
- 52 kDa
-
Gen-ID
- 54583
-
UniProt
- Q9GZT9
-
Pathways
- cAMP Metabolic Process, Warburg Effekt
Target
-