EGLN1 Antikörper (C-Term)

Produktnummer ABIN1537273

Produktdetails anti-EGLN1 Antikörper

Target: EGLN1 (Egl-9 Family Hypoxia Inducible Factor 1 (EGLN1))

Bindungsspezifität: AA 396-425, C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser EGLN1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This EGLN1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 396-425 amino acids from the C-terminal region of human EGLN1.

Klon: RB39542

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: EGLN1 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Haltbarkeit: 6 months

Details zu EGLN1

Target: EGLN1 (Egl-9 Family Hypoxia Inducible Factor 1 (EGLN1))

Andere Bezeichnung: EGLN1 (EGLN1 Produkte)

Synonyme: EGLN1 antikoerper, egln2 antikoerper, phd2 antikoerper, zgc:92314 antikoerper, AI503754 antikoerper, C1orf12 antikoerper, HIF-PH2 antikoerper, HPH-2 antikoerper, Hif-p4h-2 antikoerper, ORF13 antikoerper, Phd2 antikoerper, SM-20 antikoerper, PHD-2 antikoerper, PHD2 antikoerper, ECYT3 antikoerper, HIFPH2 antikoerper, HPH2 antikoerper, SM20 antikoerper, ZMYND6 antikoerper, egl nine homolog 1 (C. elegans) antikoerper, egl-9 family hypoxia inducible factor 1 antikoerper, egl-9 family hypoxia-inducible factor 1 S homeolog antikoerper, egl-9 family hypoxia-inducible factor 1b antikoerper, egl-9 family hypoxia-inducible factor 1 antikoerper, EGLN1 antikoerper, egln1.S antikoerper, egln1b antikoerper, Egln1 antikoerper

Hintergrund: The protein encoded by this gene catalyzes the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. HIF is a transcriptional complex that plays a central role in mammalian oxygen homeostasis. This protein functions as a cellular oxygen sensor, and under normal oxygen concentration, modification by prolyl hydroxylation is a key regulatory event that targets HIF subunits for proteasomal destruction via the von Hippel-Lindau ubiquitylation complex. Mutations in this gene are associated with erythrocytosis familial type 3 (ECYT3).

Molekulargewicht: 46021

Gen-ID: 54583

NCBI Accession: NP_071334

UniProt: Q9GZT9

Pathways: cAMP Metabolic Process, Warburg Effekt