Insulin Receptor Antikörper

Produktnummer ABIN7605279

Dieses Kaninchen Monoklonal-Antikörper erkennt spezifisch Insulin Receptor in WB, ICC und IF. Er zeigt eine Reaktivität gegenüber Human und Ratte.

Kurzübersicht für Insulin Receptor Antikörper (ABIN7605279)

Target: Insulin Receptor (INSR)

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser Insulin Receptor Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF)

Klon: GGA-9

Produktdetails anti-Insulin Receptor Antikörper

Verwendungszweck: Anti-Insulin Receptor INSR Rabbit Monoclonal Antibody

Produktmerkmale: Anti-Insulin Receptor INSR Rabbit Monoclonal Antibody (ABIN7605279). Tested in WB, ICC/IF applications. This antibody reacts with Human, Rat.

Aufreinigung: Affinity-chromatography

Immunogen: A synthesized peptide derived from human Insulin Receptor

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:1000-1:2000
ICC/IF 1:50-1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Rekonstitution: Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Konzentration: Lot specific

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol, 0.4-0.5 mg/mL BSA.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Details zu Insulin Receptor

Target: Insulin Receptor (INSR)

Andere Bezeichnung: INSR

Hintergrund:

Synonyms: Insulin receptor,IR,2.7.10.1,CD220,Insulin receptor subunit alpha,Insulin receptor subunit beta,INSR,

Tissue Specificity: Isoform Long and isoform Short are predominantly expressed in tissue targets of insulin metabolic effects: liver, adipose tissue and skeletal muscle but are also expressed in the peripheral nerve, kidney, pulmonary alveoli, pancreatic acini, placenta vascular endothelium, fibroblasts, monocytes, granulocytes, erythrocytes and skin. Isoform Short is preferentially expressed in fetal cells such as fetal fibroblasts, muscle, liver and kidney. Found as a hybrid receptor with IGF1R in muscle, heart, kidney, adipose tissue, skeletal muscle, hepatoma, fibroblasts, spleen and placenta (at protein level). Overexpressed in several tumors, including breast, colon, lung, ovary, and thyroid carcinomas. .

Molekulargewicht: 73 kDa

UniProt: P06213

Pathways: NF-kappaB Signalweg, RTK Signalweg, AMPK Signaling, Carbohydrate Homeostasis, Regulation of Cell Size, Regulation of Carbohydrate Metabolic Process, Growth Factor Binding, Negative Regulation of Transporter Activity