GDNF Antikörper

Produktnummer ABIN7604955

Dieser Kaninchen Monoklonal Antikörper detektiert spezifisch GDNF in WB und FACS. Es zeigt Reaktivität gegenüber Proben von Human, Maus und Ratte.

Kurzübersicht für GDNF Antikörper (ABIN7604955)

Target: GDNF (Glial Cell Line Derived Neurotrophic Factor (GDNF))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser GDNF Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS)

Klon: ABDB-7

Produktdetails anti-GDNF Antikörper

Verwendungszweck: Anti-GDNF Rabbit Monoclonal Antibody

Produktmerkmale: Anti-GDNF Rabbit Monoclonal Antibody (ABIN7604955). Tested in WB, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.

Aufreinigung: Affinity-chromatography

Immunogen: A synthesized peptide derived from human GDNF

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-2000
FC 1:20

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Rekonstitution: Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Konzentration: 0.5 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol, 0.4-0.5 mg/mL BSA.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Details zu GDNF

Target: GDNF (Glial Cell Line Derived Neurotrophic Factor (GDNF))

Andere Bezeichnung: GDNF

Hintergrund:

Synonyms: Glial cell line-derived neurotrophic factor,hGDNF,Astrocyte-derived trophic factor,ATF,GDNF,

Tissue Specificity: In the brain, predominantly expressed in the striatum with highest levels in the caudate and lowest in the putamen. Isoform 2 is absent from most tissues except for low levels in intestine and kidney. Highest expression of isoform 3 is found in pancreatic islets. Isoform 5 is expressed at very low levels in putamen, nucleus accumbens, prefrontal cortex, amygdala, hypothalamus and intestine. Isoform 3 is up-regulated in the middle temporal gyrus of Alzheimer disease patients while isoform 2 shows no change. .

Molekulargewicht: 28 kDa

UniProt: P39905

Pathways: RTK Signalweg, Synaptic Membrane, Tube Formation, Autophagie, Smooth Muscle Cell Migration