Annexin A2 Antikörper (N-Term)

Produktnummer ABIN7603195

Der Kaninchen Polyklonal Anti-Annexin A2-Antikörper wurde für WB und FACS validiert. Er ist geeignet, Annexin A2 in Proben von Human, Maus und Ratte zu detektieren.

Kurzübersicht für Annexin A2 Antikörper (N-Term) (ABIN7603195)

Target: Annexin A2 (ANXA2)

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Annexin A2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS)

Produktdetails anti-Annexin A2 Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: Anti-Annexin A2/ANXA2 Antibody Picoband®

Produktmerkmale: Anti-Annexin A2/ANXA2 Antibody Picoband® (ABIN7603195). Tested in WB, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human ANXA2, which shares 92.9% and 100% amino acid (aa) sequence identity with mouse and rat ANXA2, respectively.

Anwendungsinformationen

Applikationshinweise: Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
1. Huang, K.-S., Wallner, B. P., Mattaliano, R. J., Tizard, R., Burne, C., Frey, A., Hession, C., McGray, P., Sinclair, L. K., Chow, E. P., Browning, J. L., Ramachandran, K. L., Tang, J., Smart, J. E., Pepinsky, R. B. Two human 35 kd inhibitors of phospholipase A2 are related to substrates of pp60(v-src) and of the epidermal growth factor receptor/kinase. Cell 46: 191-199, 1986. 2. Huebner, K., Cannizzaro, L. A., Croce, C. M., Frey, A. Z., Wallner, B. P., Hecht, B. K., Hecht, F. Chromosome localization of the human genes for lipocortin I and the lipocortin II family. (Abstract) Cytogenet. Cell Genet. 46: 631 only, 1987. 3. Huebner, K., Cannizzaro, L. A., Frey, A. Z., Hecht, B. K., Hecht, F., Croce, C. M., Wallner, B. P. Chromosomal localization of the human genes for lipocortin I and lipocortin II. Oncogene Res. 2: 299-310, 1988.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Details zu Annexin A2

Target: Annexin A2 (ANXA2)

Andere Bezeichnung: ANXA2

Hintergrund: Annexin A2 also known as annexin II is a protein that in humans is encoded by the ANXA2 gene. This gene encodes a member of the annexin family. Members of this calcium-dependent phospholipid-binding protein family play a role in the regulation of cellular growth and in signal transduction pathways. This protein functions as an autocrine factor which heightens osteoclast formation and bone resorption. This gene has three pseudogenes located on chromosomes 4, 9 and 10, respectively. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. Annexin A2 expression has been found to correlate with resistance to treatment against various cancer forms.

Molekulargewicht: 39 kDa

Gen-ID: 302

UniProt: P07355

Pathways: S100 Proteine