Presenilin 1 Antikörper (Catalytic Subunit)

Produktnummer ABIN7602951

Dieses Kaninchen Monoklonal-Antikörper erkennt spezifisch Presenilin 1 in WB und FACS. Er zeigt eine Reaktivität gegenüber Human, Maus und Ratte.

Kurzübersicht für Presenilin 1 Antikörper (Catalytic Subunit) (ABIN7602951)

Target: Presenilin 1 (PSEN1)

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser Presenilin 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS)

Klon: AECD-16

Produktdetails anti-Presenilin 1 Antikörper

Bindungsspezifität: Catalytic Subunit

Verwendungszweck: Anti-Presenilin 1 Monoclonal Antibody

Produktmerkmale: Anti-Presenilin 1 Monoclonal Antibody (ABIN7602951). Tested in WB, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.

Aufreinigung: Affinity-chromatography

Immunogen: A synthesized peptide derived from human Presenilin 1 Probable catalytic subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (beta-amyloid precursor protein) . Requires the other members of the gamma-secretase complex to have a protease activity.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000
FC 1:10

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Rekonstitution: Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Konzentration: Lot specific

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol, 0.4-0.5 mg/mL BSA.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Details zu Presenilin 1

Target: Presenilin 1 (PSEN1)

Andere Bezeichnung: PSEN1

Hintergrund:

Synonyms: Monocyte differentiation antigen CD14 ,Myeloid cell-specific leucine-rich glycoprotein,CD14,Monocyte differentiation antigen CD14, urinary form,Monocyte differentiation antigen CD14, membrane-bound form,CD14,

Tissue Specificity: Detected on macrophages (at protein level) (PubMed:1698311). Expressed strongly on the surface of monocytes and weakly on the surface of granulocytes, also expressed by most tissue macrophages. .

Molekulargewicht: 25 kDa

UniProt: P49768

Pathways: Notch Signalweg, EGFR Signaling Pathway, Synaptic Vesicle Exocytosis, Dicarboxylic Acid Transport