WIPF1 Antikörper (C-Term)
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- Target Alle WIPF1 Antikörper anzeigen
- WIPF1 (WAS/WASL Interacting Protein Family, Member 1 (WIPF1))
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Bindungsspezifität
- C-Term
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser WIPF1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Flow Cytometry (FACS)
- Verwendungszweck
- Anti-WIPF1 Antibody Picoband®
- Kreuzreaktivität (Details)
- No cross-reactivity with other proteins.
- Produktmerkmale
- Anti-WIPF1 Antibody Picoband® (ABIN7602942). Tested in Flow Cytometry, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
- Aufreinigung
- Immunogen affinity purified.
- Immunogen
- A synthetic peptide corresponding to a sequence at the C-terminus of human WIPF1, which shares 95% amino acid (aa) sequence identity with mouse and rat WIPF1.
- Isotyp
- IgG
- Top Product
- Discover our top product WIPF1 Primärantikörper
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- Applikationshinweise
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Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
1. Al-Mousa, H., Hawwari, A., Al-Ghonaium, A., Al-Saud, B., Al-Dhekri, H., Al-Muhsen, S., Elshorbagi, S., Dasouki, M., El-Baik, L., Alseraihy, A., Ayas, M., Arnaout, R. Hematopoietic stem cell transplantation corrects WIP deficiency. (Letter) J. Allergy Clin. Immun. 139: 1039-1040, 2017. 2. Anton, I. M., de la Fuente, M. A., Sims, T. N., Freeman, S., Ramesh, N., Hartwig, J. H., Dustin, M. L., Geha, R. S. WIP deficiency reveals a differential role for WIP and the actin cytoskeleton in T and B cell activation. Immunity 16: 193-204, 2002. 3. Gross, M. B. Personal Communication. Baltimore, Md. 2/23/2012. - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- Konzentration
- 500 μg/mL
- Buffer
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- Target
- WIPF1 (WAS/WASL Interacting Protein Family, Member 1 (WIPF1))
- Andere Bezeichnung
- WIPF1 (WIPF1 Produkte)
- Hintergrund
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Synonyms: Vascular endothelial growth factor B, VEGF-B, VEGF-related factor, VRF, VEGFB, VRF
Tissue Specificity: Expressed in all tissues except liver. Highest levels found in heart, skeletal muscle and pancreas.
Background: WAS/WASL-interacting protein (WIP) is a protein that in humans is encoded by the WIPF1 gene. This gene encodes a protein that plays an important role in the organization of the actin cytoskeleton. The encoded protein binds to a region of Wiskott-Aldrich syndrome protein that is frequently mutated in Wiskott-Aldrich syndrome, an X-linked recessive disorder. Impairment of the interaction between these two proteins may contribute to the disease. Two transcript variants encoding the same protein have been identified for this gene.
- Molekulargewicht
- 56 kDa
- Gen-ID
- 7456
- UniProt
- O43516
- Pathways
- RTK Signalweg
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