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WIPF1 Antikörper (C-Term)

WIPF1 Reaktivität: Human, Maus, Ratte WB, FACS Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7602942
  • Target Alle WIPF1 Antikörper anzeigen
    WIPF1 (WAS/WASL Interacting Protein Family, Member 1 (WIPF1))
    Bindungsspezifität
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reaktivität
    • 17
    • 6
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 15
    • 2
    Kaninchen
    Klonalität
    • 15
    • 2
    Polyklonal
    Konjugat
    • 8
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser WIPF1 Antikörper ist unkonjugiert
    Applikation
    • 8
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS)
    Verwendungszweck
    Anti-WIPF1 Antibody Picoband®
    Kreuzreaktivität (Details)
    No cross-reactivity with other proteins.
    Produktmerkmale
    Anti-WIPF1 Antibody Picoband® (ABIN7602942). Tested in Flow Cytometry, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
    Aufreinigung
    Immunogen affinity purified.
    Immunogen
    A synthetic peptide corresponding to a sequence at the C-terminus of human WIPF1, which shares 95% amino acid (aa) sequence identity with mouse and rat WIPF1.
    Isotyp
    IgG
    Top Product
    Discover our top product WIPF1 Primärantikörper
  • Applikationshinweise
    Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
    1. Al-Mousa, H., Hawwari, A., Al-Ghonaium, A., Al-Saud, B., Al-Dhekri, H., Al-Muhsen, S., Elshorbagi, S., Dasouki, M., El-Baik, L., Alseraihy, A., Ayas, M., Arnaout, R. Hematopoietic stem cell transplantation corrects WIP deficiency. (Letter) J. Allergy Clin. Immun. 139: 1039-1040, 2017. 2. Anton, I. M., de la Fuente, M. A., Sims, T. N., Freeman, S., Ramesh, N., Hartwig, J. H., Dustin, M. L., Geha, R. S. WIP deficiency reveals a differential role for WIP and the actin cytoskeleton in T and B cell activation. Immunity 16: 193-204, 2002. 3. Gross, M. B. Personal Communication. Baltimore, Md. 2/23/2012.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    Konzentration
    500 μg/mL
    Buffer
    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • Target
    WIPF1 (WAS/WASL Interacting Protein Family, Member 1 (WIPF1))
    Andere Bezeichnung
    WIPF1 (WIPF1 Produkte)
    Hintergrund

    Synonyms: Vascular endothelial growth factor B, VEGF-B, VEGF-related factor, VRF, VEGFB, VRF

    Tissue Specificity: Expressed in all tissues except liver. Highest levels found in heart, skeletal muscle and pancreas.

    Background: WAS/WASL-interacting protein (WIP) is a protein that in humans is encoded by the WIPF1 gene. This gene encodes a protein that plays an important role in the organization of the actin cytoskeleton. The encoded protein binds to a region of Wiskott-Aldrich syndrome protein that is frequently mutated in Wiskott-Aldrich syndrome, an X-linked recessive disorder. Impairment of the interaction between these two proteins may contribute to the disease. Two transcript variants encoding the same protein have been identified for this gene.

    Molekulargewicht
    56 kDa
    Gen-ID
    7456
    UniProt
    O43516
    Pathways
    RTK Signalweg
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