BHMT Antikörper (AA 80-406)

Produktnummer ABIN7602515

Dieser Anti-BHMT Antikörper ist ein Kaninchen Polyklonal Antikörper zur Detektion von BHMT in WB, ELISA und FACS. Geeignet für Human, Maus, Ratte und Affe.

Kurzübersicht für BHMT Antikörper (AA 80-406) (ABIN7602515)

Target: BHMT (Betaine--Homocysteine S-Methyltransferase (BHMT))

Reaktivität: Human, Maus, Ratte, Affe

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BHMT Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Produktdetails anti-BHMT Antikörper

Bindungsspezifität: AA 80-406

Verwendungszweck: Anti-BHMT Antibody Picoband®

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Produktmerkmale: Anti-BHMT Antibody Picoband® (ABIN7602515). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human, Monkey, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human BHMT recombinant protein (Position: E80-Q406).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.1-0.25 μg/mL, Mouse, Rat, Monkey
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Garrow, T. A. Purification, kinetic properties, and cDNA cloning of mammalian betaine-homocysteine methyltransferase. J. Biol. Chem. 271: 22831-22838, 1996. 2. Li, F., Feng, Q., Lee, C., Wang, S., Pelleymounter, L. L., Moon, I., Eckloff, B. W., Wieben, E. D., Schaid, D. J., Yee, V., Weinshilboum, R. M. Human betaine-homocysteine methyltransferase (BHMT) and BHMT2: common gene sequence variation and functional characterization. Molec. Genet. Metab. 94: 326-335, 2008. 3. Park, E. I., Garrow, T. A. Interaction between dietary methionine and methyl donor intake on rat liver betaine-homocysteine methyltransferase gene expression and organization of the human gene. J. Biol. Chem. 274: 7816-7824, 1999.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.005 mg Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Details zu BHMT

Target: BHMT (Betaine--Homocysteine S-Methyltransferase (BHMT))

Andere Bezeichnung: BHMT

Hintergrund:

Synonyms: Neurocan core protein, Chondroitin sulfate proteoglycan 3, NCAN, CSPG3, NEUR,

Tissue Specificity: Brain.

Background: This gene encodes a cytosolic enzyme that catalyzes the conversion of betaine and homocysteine to dimethylglycine and methionine, respectively. Defects in this gene could lead to hyperhomocyst (e)inemia, but such a defect has not yet been observed.

Molekulargewicht: 45 kDa

Gen-ID: 635

UniProt: Q93088

Pathways: Methionine Biosynthetic Process