PRP19 Antikörper (AA 51-359)

Produktnummer ABIN7601932

Der Kaninchen Polyklonal Anti-PRP19-Antikörper wurde für WB, ELISA, FACS, IF und ICC validiert. Er ist geeignet, PRP19 in Proben von Human zu detektieren.

Kurzübersicht für PRP19 Antikörper (AA 51-359) (ABIN7601932)

Target: PRP19 (PRPF19) (Pre-mRNA Processing Factor 19 (PRPF19))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PRP19 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunofluorescence (IF), Immunocytochemistry (ICC)

Produktdetails anti-PRP19 Antikörper

Bindungsspezifität: AA 51-359

Verwendungszweck: Anti-PRPF19 Antibody Picoband®

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Produktmerkmale: Anti-PRPF19 Antibody Picoband® (ABIN7601932). Tested in ELISA, Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human PRPF19 recombinant protein (Position: Q51-H359).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.25-0.5 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Beck, B. D., Park, S.-J., Lee, Y.-J., Roman, Y., Hromas, R. A., Lee, S.-H. Human Pso4 is a Metnase (SETMAR)-binding partner that regulates Metnase function in DNA repair. J. Biol. Chem. 283: 9023-9030, 2008. 2. Gross, M. B. Personal Communication. Baltimore, Md. 9/6/2016. 3. Mahajan, K. N., Mitchell, B. S. Role of human Pso4 in mammalian DNA repair and association with terminal deoxynucleotidyl transferase. Proc. Nat. Acad. Sci. 100: 10746-10751, 2003.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Details zu PRP19

Target: PRP19 (PRPF19) (Pre-mRNA Processing Factor 19 (PRPF19))

Andere Bezeichnung: PRPF19

Hintergrund:

Synonyms: PH domain leucine-rich repeat-containing protein phosphatase 1, Pleckstrin homology domain-containing family E member 1, PH domain-containing family E member 1, Suprachiasmatic nucleus circadian oscillatory protein, hSCOP, PHLPP1, KIAA0606, PHLPP, PLEKHE1, SCOP

Tissue Specificity: Monocyte/macrophage specific.

Background: Pre-mRNA-processing factor 19 is a protein that in humans is encoded by the PRPF19 gene. Enables identical protein binding activity and ubiquitin-ubiquitin ligase activity. Involved in several processes, including DNA damage checkpoint signaling, cellular protein metabolic process, and mRNA splicing, via spliceosome. Acts upstream of or within protein polyubiquitination. Located in cytoplasm, nuclear speck, and site of double-strand break. Part of Prp19 complex and U2-type catalytic step 2 spliceosome. Colocalizes with DNA replication factor A complex.

Molekulargewicht: 54 kDa

Gen-ID: 27339

Pathways: Ribonucleoprotein Complex Subunit Organization