PRR5 Antikörper (AA 45-366)

Produktnummer ABIN7601773

Der Kaninchen Polyklonal anti-PRR5 Antikörper wird verwendet zum Nachweis von PRR5 in Proben von Human. Er wurde validiert für WB, ELISA und FACS.

Kurzübersicht für PRR5 Antikörper (AA 45-366) (ABIN7601773)

Target: PRR5 (Proline Rich 5 (Renal) (PRR5))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PRR5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Produktdetails anti-PRR5 Antikörper

Bindungsspezifität: AA 45-366

Verwendungszweck: Anti-PRR5 Antibody

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Produktmerkmale: Anti-PRR5 Antibody. Tested in ELISA, WB, Flow Cytometry applications. This antibody reacts with Human.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human PRR5 recombinant protein (Position: S45-D366).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.25-0.5 μg/mL, Human Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human ELISA, 0.1-0.5 μg/mL, -

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu PRR5

Target: PRR5 (Proline Rich 5 (Renal) (PRR5))

Andere Bezeichnung: PRR5

Hintergrund:

Background: This gene encodes a protein with a proline-rich domain. This gene is located in a region of chromosome 22 reported to contain a tumor suppressor gene that may be involved in breast and colorectal tumorigenesis. The protein is a component of the mammalian target of rapamycin complex 2 (mTORC2), and it regulates platelet-derived growth factor (PDGF) receptor beta expression and PDGF signaling to Akt and S6K1. Alternative splicing and the use of alternative promoters results in transcripts encoding different isoforms. Read-through transcripts from this gene into the downstream Rho GTPase activating protein 8 (ARHGAP8) gene also exist, which led to the original description of PRR5 and ARHGAP8 being a single gene.

Gene Full Name: proline rich 5

Molekulargewicht: 39 kDa

Gen-ID: 55615

UniProt: P85299

Pathways: PI3K-Akt Signalweg