MYLK3 Antikörper (AA 34-812)

Produktnummer ABIN7601404

Der Kaninchen Polyklonal Anti-MYLK3-Antikörper wurde für WB, ELISA und FACS validiert. Er ist geeignet, MYLK3 in Proben von Human zu detektieren.

Kurzübersicht für MYLK3 Antikörper (AA 34-812) (ABIN7601404)

Target: MYLK3 (Myosin Light Chain Kinase 3 (MYLK3))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MYLK3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Produktdetails anti-MYLK3 Antikörper

Bindungsspezifität: AA 34-812

Verwendungszweck: Anti-MYLK3 Antibody Picoband®

Produktmerkmale: Anti-MYLK3 Antibody Picoband® (ABIN7601404). Tested in WB, Flow Cytometry, ELISA applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human MYLK3 recombinant protein (Position: E34-K812). Human MYLK3 shares 68.8% and 66.8% amino acid (aa) sequence identity with mouse and rat MYLK3, respectively.

Anwendungsinformationen

Applikationshinweise: Western blot, 0.25-0.5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Chan, J. Y., Takeda, M., Briggs, L. E., Graham, M. L., Lu, J. T., Horikoshi, N., Weinberg, E. O., Aoki, H., Sato, N., Chien, K. R., Kasahara, H. Identification of cardiac-specific myosin light chain kinase. Circ. Res. 102: 571-580, 2008. 2. Hartz, P. A. Personal Communication. Baltimore, Md. 6/30/2008. 3. Seguchi, O., Takashima, S., Yamazaki, S., Asakura, M., Asano, Y., Shintani, Y., Wakeno, M., Minamino, T., Kondo, H., Furukawa, H., Nakamuru, K., Naito, A., Takahashi, T., Ohtsuka, T., Kawakami, K., Isomura, T., Kitamura, S., Tomoike, H., Mochizuki, N., Kitakaze, M. A cardiac myosin light chain kinase regulates sarcomere assembly in the vertebrate heart. J. Clin. Invest. 117: 2812-2824, 2007.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Details zu MYLK3

Target: MYLK3 (Myosin Light Chain Kinase 3 (MYLK3))

Andere Bezeichnung: MYLK3

Hintergrund: Myosin light chain kinase 3 also known as MYLK3, is an enzyme which in humans is encoded by the MYLK3 gene. Phosphorylation of cardiac myosin heavy chains (see MYH7B, MIM 609928) and light chains (see MYL2, MIM 160781) by a kinase, such as MYLK3, potentiates the force and rate of cross-bridge recruitment in cardiac myocytes.

Molekulargewicht: 100 kDa

Gen-ID: 91807

Pathways: Regulation of Muscle Cell Differentiation