CD79a Antikörper (AA 29-220)

Produktnummer ABIN7601110

Der Kaninchen Polyklonal Anti-CD79a Antikörper wurde für FACS, IF, WB, IHC und ELISA validiert. Er ist geeignet, CD79a in Proben von Maus und Ratte zu detektieren.

Kurzübersicht für CD79a Antikörper (AA 29-220) (ABIN7601110)

Target: CD79a (CD79A) (B-cell antigen receptor complex-associated protein alpha chain (CD79A))

Reaktivität: Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CD79a Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Immunofluorescence (IF), Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Produktdetails anti-CD79a Antikörper

Bindungsspezifität: AA 29-220

Verwendungszweck: Anti-Cd79a Antibody Picoband®

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Produktmerkmale: Anti-Cd79a Antibody Picoband® (ABIN7601110). Tested in ELISA, Flow Cytometry, IF, IHC, WB applications. This antibody reacts with Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived mouse Cd79a recombinant protein (Position: L29-P220).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.25-0.5 μg/mL, Mouse, Rat
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Mouse, Rat
Immunofluorescence, 2 μg/mL, Mouse, Rat
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Mouse
ELISA, 0.1-0.5 μg/mL, -
1. Ha, H., Kubagawa, H., Burrows, P. D. Molecular cloning and expression pattern of a human gene homologous to the murine mb-1 gene. J. Immun. 148: 1526-1531, 1992. 2. Hashimoto, S., Mohrenweiser, H. W., Gregersen, P. K., Chiorazzi, N. Chromosomal localization, genomic structure, and allelic polymorphism of the human CD79a (Ig-alpha/mb-1) gene. Immunogenetics 40: 287-295, 1994. 3. Minegishi, Y., Coustan-Smith, E., Rapalus, L., Ersoy, F., Campana, D., Conley, M. E. Mutations in Ig-alpha (CD79a) result in a complete block in B-cell development. J. Clin. Invest. 104: 1115-1121, 1999.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na₂HPO₄, 0.01 mg NaN₃.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Details zu CD79a

Target: CD79a (CD79A) (B-cell antigen receptor complex-associated protein alpha chain (CD79A))

Andere Bezeichnung: Cd79a

Hintergrund:

Synonyms: B-cell antigen receptor complex-associated protein alpha chain, Ig-alpha, MB-1 membrane glycoprotein, Membrane-bound immunoglobulin-associated protein, Surface IgM-associated protein, CD79a, Cd79a, Iga, Mb-1

Tissue Specificity: B-cells.

Background: Cluster of differentiation CD79A also known as B-cell antigen receptor complex-associated protein alpha chain and MB-1 membrane glycoprotein, is a protein that in humans is encoded by the CD79A gene. It is mapped to 7 A3, 7 13.49 cM. The B lymphocyte antigen receptor is a multimeric complex that includes the antigen-specific component, surface immunoglobulin (Ig). Surface Ig non-covalently associates with two other proteins, Ig-alpha and Ig-beta, which are necessary for expression and function of the B-cell antigen receptor. This gene encodes the Ig-alpha protein of the B-cell antigen component. Alternatively spliced transcript variants encoding different isoforms have been described.

Molekulargewicht: 25-30 kDa

Gen-ID: 12518

UniProt: P11911

Pathways: BCR Signaling