Poliovirus Receptor Antikörper (AA 28-331)

Produktnummer ABIN7601070

Dieser Maus Monoklonal Antikörper detektiert spezifisch Poliovirus Receptor in WB, IHC und FACS. Es zeigt Reaktivität gegenüber Proben von Human und Maus.

Kurzübersicht für Poliovirus Receptor Antikörper (AA 28-331) (ABIN7601070)

Target: Poliovirus Receptor (PVR)

Reaktivität: Human, Maus

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Poliovirus Receptor Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)

Klon: 3B11E9

Produktdetails anti-Poliovirus Receptor Antikörper

Bindungsspezifität: AA 28-331

Verwendungszweck: Anti-Poliovirus Receptor/PVR Antibody (monoclonal, 3B11E9)

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Produktmerkmale: Anti-Poliovirus Receptor/PVR Antibody.(monoclonal, 3B11E9)-3. Tested in Flow Cytometry, IHC, WB applications. This antibody reacts with Human, Mouse.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human Poliovirus Receptor/PVR recombinant protein (Position: D28-E331).

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise: Western blot, 0.25-0.5 μg/mL, Human Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human, Mouse Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu Poliovirus Receptor

Target: Poliovirus Receptor (PVR)

Andere Bezeichnung: PVR

Hintergrund:

Background: CD155 (cluster of differentiation 155) also known as the poliovirus receptor is a protein that in humans is encoded by the PVR gene. The protein encoded by this gene is a transmembrane glycoprotein belonging to the immunoglobulin superfamily. The external domain mediates cell attachment to the extracellular matrix molecule vitronectin, while its intracellular domain interacts with the dynein light chain Tctex-1/DYNLT1. The gene is specific to the primate lineage, and serves as a cellular receptor for poliovirus in the first step of poliovirus replication. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene Full Name: PVR cell adhesion molecule

Molekulargewicht: 70-80 kDa

Gen-ID: 5817

UniProt: P15151

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cell-Cell Junction Organization, Cancer Immune Checkpoints, SARS-CoV-2 Protein Interaktom