DLL4 Antikörper (AA 27-678)
Kurzübersicht für DLL4 Antikörper (AA 27-678) (ABIN7601029)
Target
Alle DLL4 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 27-678
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Verwendungszweck
- Anti-DLL4 Antibody Picoband®
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Kreuzreaktivität (Details)
- No cross-reactivity with other proteins.
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Produktmerkmale
- Anti-DLL4 Antibody Picoband® (ABIN7601029). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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Aufreinigung
- Immunogen affinity purified.
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Immunogen
- E.coli-derived human DLL4 recombinant protein (Position: S27-E678).
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Isotyp
- IgG
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Applikationshinweise
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Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Flow Cytometry (Fixed), 1-3 μg/1x1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. "Entrez Gene: DLL4 delta-like 4 (Drosophila)". 2. Dorsch M, Zheng G, Yowe D, et al. (2002). "Ectopic expression of Delta4 impairs hematopoietic development and leads to lymphoproliferative disease". Blood. 100 (6): 2046-55. 3. Shutter JR, Scully S, Fan W, Richards WG, Kitajewski J, Deblandre GA, Kintner CR, Stark KL (Jul 2000). "Dll4, a novel Notch ligand expressed in arterial endothelium". Genes Dev. 14 (11): 1313-8. -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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Konzentration
- 500 μg/mL
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Buffer
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- DLL4 (delta-Like 4 (DLL4))
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Andere Bezeichnung
- DLL4
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Hintergrund
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Synonyms: NF-kappa-B essential modulator,NEMO,FIP-3,IkB kinase-associated protein 1,IKKAP1,Inhibitor of nuclear factor kappa-B kinase subunit gamma,I-kappa-B kinase subunit gamma,IKK-gamma,IKKG,IkB kinase subunit gamma,NF-kappa-B essential modifier,IKBKG,FIP3, NEMO,
Tissue Specificity: Heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas.
Background: Delta-like 4 is a protein that in humans is encoded by the DLL4 gene. It is mapped to 15q15.1. This gene is a homolog of the Drosophila delta gene. The delta gene family encodes Notch ligands that are characterized by a DSL domain, EGF repeats, and a transmembrane domain. And this gene plays an important role in promoting Th17 effector activity during mycobacterial challenge.
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Molekulargewicht
- 80 kDa
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Gen-ID
- 54567
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Pathways
- Notch Signalweg
Target
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