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DLL4 Antikörper (AA 27-678)

Der Kaninchen Polyklonal Anti-DLL4-Antikörper wurde für WB, ELISA und FACS validiert. Er ist geeignet, DLL4 in Proben von Human, Maus und Ratte zu detektieren.
Produktnummer ABIN7601029

Kurzübersicht für DLL4 Antikörper (AA 27-678) (ABIN7601029)

Target

Alle DLL4 Antikörper anzeigen
DLL4 (delta-Like 4 (DLL4))

Reaktivität

  • 59
  • 41
  • 18
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
Human, Maus, Ratte

Wirt

  • 63
  • 19
  • 9
  • 5
  • 1
Kaninchen

Klonalität

  • 64
  • 32
  • 1
Polyklonal

Konjugat

  • 59
  • 9
  • 4
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser DLL4 Antikörper ist unkonjugiert

Applikation

  • 49
  • 33
  • 23
  • 15
  • 13
  • 13
  • 11
  • 10
  • 9
  • 5
  • 5
  • 4
  • 4
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA, Flow Cytometry (FACS)
  • Bindungsspezifität

    • 15
    • 7
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 27-678

    Verwendungszweck

    Anti-DLL4 Antibody Picoband®

    Kreuzreaktivität (Details)

    No cross-reactivity with other proteins.

    Produktmerkmale

    Anti-DLL4 Antibody Picoband® (ABIN7601029). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    Aufreinigung

    Immunogen affinity purified.

    Immunogen

    E.coli-derived human DLL4 recombinant protein (Position: S27-E678).

    Isotyp

    IgG
  • Applikationshinweise

    Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
    Flow Cytometry (Fixed), 1-3 μg/1x1x106 cells, Human
    ELISA, 0.1-0.5 μg/mL, -
    1. "Entrez Gene: DLL4 delta-like 4 (Drosophila)". 2. Dorsch M, Zheng G, Yowe D, et al. (2002). "Ectopic expression of Delta4 impairs hematopoietic development and leads to lymphoproliferative disease". Blood. 100 (6): 2046-55. 3. Shutter JR, Scully S, Fan W, Richards WG, Kitajewski J, Deblandre GA, Kintner CR, Stark KL (Jul 2000). "Dll4, a novel Notch ligand expressed in arterial endothelium". Genes Dev. 14 (11): 1313-8.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    Konzentration

    500 μg/mL

    Buffer

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • Target

    DLL4 (delta-Like 4 (DLL4))

    Andere Bezeichnung

    DLL4

    Hintergrund

    Synonyms: NF-kappa-B essential modulator,NEMO,FIP-3,IkB kinase-associated protein 1,IKKAP1,Inhibitor of nuclear factor kappa-B kinase subunit gamma,I-kappa-B kinase subunit gamma,IKK-gamma,IKKG,IkB kinase subunit gamma,NF-kappa-B essential modifier,IKBKG,FIP3, NEMO,

    Tissue Specificity: Heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas.

    Background: Delta-like 4 is a protein that in humans is encoded by the DLL4 gene. It is mapped to 15q15.1. This gene is a homolog of the Drosophila delta gene. The delta gene family encodes Notch ligands that are characterized by a DSL domain, EGF repeats, and a transmembrane domain. And this gene plays an important role in promoting Th17 effector activity during mycobacterial challenge.

    Molekulargewicht

    80 kDa

    Gen-ID

    54567

    Pathways

    Notch Signalweg
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