DLL4 Antikörper (delta-Like 4) (Internal Region)

Details for Product anti-DLL4 Antibody No. ABIN129625, Anbieter: Anmelden zum Anzeigen
Antigen
  • hdelta2
  • Delta4
  • si:ch211-244p18.5
  • zgc:136596
  • delta like canonical Notch ligand 4
  • delta-like 4 (Drosophila)
  • DLL4
  • Dll4
  • dll4
Epitop
Internal Region
10
10
5
5
4
4
4
4
4
3
3
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
Reaktivität
Human
152
73
47
4
4
4
3
3
3
2
2
1
1
1
Wirt
Kaninchen
85
63
22
13
7
Klonalität
Polyklonal
Konjugat
Dieser DLL4 Antikörper ist unkonjugiert
9
7
6
4
4
3
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Applikation
Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
94
69
64
39
19
13
9
8
6
5
5
4
2
2
2
2
1
1
1
Optionen
Hersteller
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Hersteller Produkt- Nr.
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Immunogen This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to an of Human DELTA-4.
Isotyp IgG
Kreuzreaktivität Maus, Ratte (Rattus)
Produktmerkmale Concentration Definition: by UV absorbance at 280 nm
Plasmids, Primers & others Plasmide, Primers & weitere DLL4 products on genomics-online (e.g. as negative or positive controls)
Antigen
Andere Bezeichnung DELTA-4 (DLL4 Antibody Abstract)
Hintergrund DELTA-4 (also called delta 4 precursor, delta ligand 4 precursor, Delta-like protein 4, DLL4, Drosophila Delta homolog 4 and notch ligand DLL4 precursor) is a homolog of the Drosophila delta protein. The delta gene family encodes Notch ligands that are characterized by a DSL domain, EGF repeats, and a transmembrane domain.  DELTA-4  plays a role in the Notch signaling pathway and activates Notch-1 and Notch-4. DELTA-4 is a membrane protein that is expressed in the vascular endothelium.
Synonyms: DELTA-4, delta 4 precursor, delta ligand 4 precursor, Delta-like protein 4, DLL4, Drosophila Delta homolog 4 and notch ligand DLL4 precursor
Gen-ID 54567, 9506545
UniProt Q9NR61
Pathways Notch Signalweg
Applikations-hinweise Anti-DELTA-4 has been tested for use in ELISA, immunohistochemistry and western blotting.  Specific conditions for reactivity should be optimized by the end user. Expect a band approximately 74 kDa in size corresponding to DELTA-4 by western blotting in the appropriate cell lysate or extract. For best results use Goat Serum as blocking agent in western blotting.
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 0.88 mg/mL
Buffer 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Bilder des Herstellers
Immunohistochemistry (IHC) image for anti-delta-Like 4 (DLL4) (Internal Region) antibody (ABIN129625) Affinity Purified anti-Delta-4 antibody was used at 20 µg/ml to detect Delta-4 in a v...
Immunohistochemistry (IHC) image for anti-delta-Like 4 (DLL4) (Internal Region) antibody (ABIN129625) Immunohistochemistry. antibodies-online's Affinity Purified anti-Delta-4 antibody was...
 image for anti-delta-Like 4 (DLL4) (Internal Region) antibody (ABIN129625) anti-delta-Like 4 (DLL4) (Internal Region) antibody (Image 3)
 image for anti-delta-Like 4 (DLL4) (Internal Region) antibody (ABIN129625) anti-delta-Like 4 (DLL4) (Internal Region) antibody (Image 4)
ELISA image for anti-delta-Like 4 (DLL4) (Internal Region) antibody (ABIN129625) ELISA results of purified Rabbit anti-DELTA-4 Antibody tested against BSA-conjugated ...
Western Blotting (WB) image for anti-delta-Like 4 (DLL4) (Internal Region) antibody (ABIN129625) Western Blot of Rabbit anti-DELTA-4 antibody. Lane 1: Mouse Pancreas Whole Cell Lysat...
Western Blotting (WB) image for anti-delta-Like 4 (DLL4) (Internal Region) antibody (ABIN129625) Western Blot of Rabbit anti-Delta-4 antibody. Lane 1: mouse pancreatic tissue. Load: ...
 image for anti-delta-Like 4 (DLL4) (Internal Region) antibody (ABIN129625) Affinity Purified anti-Delta-4 antibody was used at 20 µg/ml to detect Delta-4 in a v...
Produkt verwendet in: Zhang, Zeng, Zhang, Jiao, Li, Jing, Ouyang, Yuan, Chai, Che, Zhang, Yang: "Suppressor of cytokine signaling 3 promotes bone marrow cells to differentiate into CD8+ T lymphocytes in lung tissue via up-regulating Notch1 expression." in: Cancer research, Vol. 69, Issue 4, pp. 1578-86, 2009 (PubMed).

Indraccolo, Minuzzo, Masiero, Pusceddu, Persano, Moserle, Reboldi, Favaro, Mecarozzi, Di Mario, Screpanti, Ponzoni, Doglioni, Amadori: "Cross-talk between tumor and endothelial cells involving the Notch3-Dll4 interaction marks escape from tumor dormancy." in: Cancer research, Vol. 69, Issue 4, pp. 1314-23, 2009 (PubMed).

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