DLL4 Antikörper (AA 44-345)

Produktnummer ABIN7149653

Produktdetails anti-DLL4 Antikörper

Target: DLL4 (delta-Like 4 (DLL4))

Bindungsspezifität: AA 44-345

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DLL4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Delta-like protein 4 protein (44-345AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: WB:1:500-1:5000, IF:1:50-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu DLL4

Target: DLL4 (delta-Like 4 (DLL4))

Andere Bezeichnung: DLL4 (DLL4 Produkte)

Synonyme: hdelta2 antikoerper, Delta4 antikoerper, si:ch211-244p18.5 antikoerper, zgc:136596 antikoerper, delta like canonical Notch ligand 4 antikoerper, delta-like 4 (Drosophila) antikoerper, DLL4 antikoerper, Dll4 antikoerper, dll4 antikoerper

Hintergrund:

Background: Involved in the Notch signaling pathway as Notch ligand (PubMed:11134954). Activates NOTCH1 and NOTCH4. Involved in angiogenesis, negatively regulates endothelial cell proliferation and migration and angiogenic sprouting (PubMed:20616313). Essential for retinal progenitor proliferation. Required for suppressing rod fates in late retinal progenitors as well as for proper generation of other retinal cell types (By similarity). During spinal cord neurogenesis, inhibits V2a interneuron fate (PubMed:17728344).

Aliases: AOS6 antibody, Delta 4 antibody, delta 4 precursor antibody, Delta ligand 4 antibody, delta ligand 4 precursor antibody, Delta like 4 antibody, Delta like 4 homolog antibody, Delta like 4 protein antibody, Delta like canonical Notch ligand 4 antibody, Delta like protein 4 antibody, Delta-like 4 (Drosophila) antibody, Delta-like protein 4 antibody, Delta4 antibody, DLL 4 antibody, Dll4 antibody, DLL4_HUMAN antibody, Drosophila Delta homolog 4 antibody, hdelta2 antibody, Homeobox protein DLL-4 antibody, MGC126344 antibody, Notch ligand delta 2 antibody, Notch ligand DLL4 antibody, Notch ligand DLL4 precursor antibody, XDLL-4 antibody

UniProt: Q9NR61

Pathways: Notch Signalweg