PRTN3 Antikörper (AA 23-241)

Produktnummer ABIN7600742

Dieses Anti-PRTN3-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von PRTN3 in WB, IHC, ELISA und FACS. Geeignet für Human.

Kurzübersicht für PRTN3 Antikörper (AA 23-241) (ABIN7600742)

Target: PRTN3 (Proteinase 3 (PRTN3))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PRTN3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS)

Produktdetails anti-PRTN3 Antikörper

Bindungsspezifität: AA 23-241

Verwendungszweck: Anti-PRTN3 Antibody Picoband®

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Produktmerkmale: Anti-PRTN3 Antibody Picoband® (ABIN7600742). Tested in ELISA, IHC, WB, Flow Cytometry applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human PRTN3 recombinant protein (Position: A23-D241).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.25-0.5 μg/mL, Human
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Belaaouaj, A., Walsh, B. C., Jenkins, N. A., Copeland, N. G., Shapiro, S. D. Characterization of the mouse neutrophil elastase gene and localization to chromosome 10. Mammalian Genome 8: 5-8, 1997. 2. Campanelli, D., Melchior, M., Fu, Y., Nakata, M., Shuman, H., Nathan, C., Gabay, J. E. Cloning of cDNA for proteinase 3: a serine protease, antibiotic, and autoantigen from human neutrophils. J. Exp. Med. 172: 1709-1715, 1990. 3. Davies, D. J., Moran, J. E., Niall, J. F., Ryan, G. B. Segmental necrotising glomerulonephritis with antineutrophil antibody: possible arbovirus aetiology. Brit. Med. J. 285: 606 only, 1982.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Details zu PRTN3

Target: PRTN3 (Proteinase 3 (PRTN3))

Andere Bezeichnung: PRTN3

Hintergrund:

Synonyms: AF4/FMR2 family member 4,ALL1-fused gene from chromosome 5q31 protein,Protein AF-5q31,Major CDK9 elongation factor-associated protein,AFF4,AF5Q31, MCEF,HSPC092,

Tissue Specificity: Ubiquitously expressed. Strongly expressed in heart, placenta, skeletal muscle, pancreas and to a lower extent in brain. .

Background: Proteinase 3, also known as PRTN3, is an enzyme that in humans is encoded by the PRTN3 gene. Enables enzyme binding activity, serine-type endopeptidase activity, and signaling receptor binding activity. Involved in several processes, including mature conventional dendritic cell differentiation, membrane protein ectodomain proteolysis, and neutrophil extravasation. Located in azurophil granule lumen, cytosol, and plasma membrane raft. Colocalizes with plasma membrane.

Molekulargewicht: 32 kDa

Gen-ID: 5657

UniProt: P24158