PRTN3 Antikörper (pArg3)
Kurzübersicht für PRTN3 Antikörper (pArg3) (ABIN7269719)
Target
Alle PRTN3 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 28-170, pArg3
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Verwendungszweck
- Proteinase 3/PR3 Rabbit pAb
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Sequenz
- IVGGHEAQPH SRPYMASLQM RGNPGSHFCG GTLIHPSFVL TAAHCLRDIP QRLVNVVLGA HNVRTQEPTQ QHFSVAQVFL NNYDAENKLN DVLLIQLSSP ANLSASVATV QLPQQDQPVP HGTQCLAMGW GRVGAHDPPA QVL
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Kreuzreaktivität
- Ratte
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Produktmerkmale
- Polyclonal Antibodies
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Aufreinigung
- Affinity purification
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Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 28-170 of human Proteinase 3/PR3 (NP_002768.3).
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Isotyp
- IgG
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Applikationshinweise
- WB,1:500 - 1:2000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- PRTN3 (Proteinase 3 (PRTN3))
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Andere Bezeichnung
- PRTN3
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Hintergrund
- Serine protease that degrades elastin, fibronectin, laminin, vitronectin, and collagen types I, III, and IV (in vitro. By cleaving and activating receptor F2RL1/PAR-2, enhances endothelial cell barrier function and thus vascular integrity during neutrophil transendothelial migration. May play a role in neutrophil transendothelial migration, probably when associated with CD177.,ACPA,AGP7,C-ANCA,CANCA,MBN,MBT,NP-4,NP4,P29,PR-3,PR3,PRTN3,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Extracellular Matrix,Collagen,PRTN3
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Gen-ID
- 5657
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UniProt
- P24158
Target
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