SETDB2 Antikörper (AA 20-714)
Kurzübersicht für SETDB2 Antikörper (AA 20-714) (ABIN7600560)
Target
Alle SETDB2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Bindungsspezifität
- AA 20-714
-
Verwendungszweck
- Anti-CLLD8/Setdb2 Antibody
-
Kreuzreaktivität (Details)
- No cross-reactivity with other proteins.
-
Produktmerkmale
- Anti-CLLD8/Setdb2 Antibody (ABIN7600560). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Mouse, Rat. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.
-
Aufreinigung
- Immunogen affinity purified.
-
Immunogen
- E.coli-derived rat CLLD8/Setdb2 recombinant protein (Position: K20-I714).
-
Isotyp
- IgG
-
-
-
-
Applikationshinweise
-
Western blot, 0.25-0.5 μg/mL, Mouse, Rat
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Mouse, Rat
ELISA, 0.1-0.5 μg/mL, Rat
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Lyophilized
-
Rekonstitution
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
-
Konzentration
- 500 μg/mL
-
Buffer
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
-
Lagerung
- 4 °C,-20 °C
-
Informationen zur Lagerung
-
At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
-
-
- SETDB2 (SET Domain, Bifurcated 2 (SETDB2))
-
Andere Bezeichnung
- Setdb2
-
Hintergrund
-
Synonyms: Histone-lysine N-methyltransferase SETDB2, Chronic lymphocytic leukemia deletion region gene 8 protein, Lysine N-methyltransferase 1F, SET domain bifurcated 2, SETDB2, C13orf4, CLLD8, KMT1F
Tissue Specificity: Highly expressed in reproductive organs, such as testis, ovary and prostate.
Background: SET domain bifurcated histone lysine methyltransferase 2 is a protein in humans encoded by the SETDB2 gene. It is mapped to 13q14.2. This gene encodes a member of a family of proteins that contain a methyl-CpG-binding domain (MBD) and a SET domain and function as histone methyltransferases. This protein is recruited to heterochromatin and plays a role in the regulation of chromosome segregation. This region is commonly deleted in chronic lymphocytic leukemia. Naturally-occuring readthrough transcription occurs from this gene to the downstream PHF11 (PHD finger protein 11) gene. Alternative splicing results in multiple transcript variants.
-
Molekulargewicht
- 100 kDa
-
Gen-ID
- 100361710
Target
-