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RRP8 Antikörper (AA 199-456)

Der Kaninchen Polyklonal Anti-RRP8-Antikörper wurde für WB, ELISA, IF, ICC und FACS validiert. Er ist geeignet, RRP8 in Proben von Human, Ratte und Maus zu detektieren.
Produktnummer ABIN7600459

Kurzübersicht für RRP8 Antikörper (AA 199-456) (ABIN7600459)

Target

Alle RRP8 Antikörper anzeigen
RRP8 (Ribosomal RNA Processing 8 (RRP8))

Reaktivität

  • 23
  • 11
  • 10
  • 4
  • 4
  • 4
  • 3
  • 2
  • 1
  • 1
Human, Ratte, Maus

Wirt

  • 21
  • 2
Kaninchen

Klonalität

  • 23
Polyklonal

Konjugat

  • 16
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser RRP8 Antikörper ist unkonjugiert

Applikation

  • 14
  • 5
  • 4
  • 3
  • 2
  • 2
  • 1
Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC), Flow Cytometry (FACS)
  • Bindungsspezifität

    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 199-456

    Verwendungszweck

    Anti-RRP8 Antibody Picoband®

    Kreuzreaktivität (Details)

    No cross-reactivity with other proteins.

    Produktmerkmale

    Anti-RRP8 Antibody Picoband® (ABIN7600459). Tested in ELISA, Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    Aufreinigung

    Immunogen affinity purified.

    Immunogen

    E.coli-derived human RRP8 recombinant protein (Position: K199-R456).

    Isotyp

    IgG
  • Applikationshinweise

    Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
    Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
    ELISA, 0.1-0.5 μg/mL, -
    1. Hartz, P. A. Personal Communication. Baltimore, Md. 5/29/2014. 2. Ishikawa, K., Nagase, T., Nakajima, D., Seki, N., Ohira, M., Miyajima, N., Tanaka, A., Kotani, H., Nomura, N., Ohara, O. Prediction of the coding sequences of unidentified human genes. VIII. 78 new cDNA clones from brain which code for large proteins in vitro. DNA Res. 4: 307-313, 1997. 3. Murayama, A., Ohmori, K., Fujimura, A., Minami, H., Yasuzawa-Tanaka, K., Kuroda, T., Oie, S., Daitoku, H., Okuwaki, M., Nagata, K., Fukamizu, A., Kimura, K., Shimizu, T., Yanagisawa, J. Epigenetic control of rDNA loci in response to intracellular energy status. Cell 133: 627-639, 2008.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    Konzentration

    500 μg/mL

    Buffer

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • Target

    RRP8 (Ribosomal RNA Processing 8 (RRP8))

    Andere Bezeichnung

    RRP8

    Hintergrund

    Synonyms: Interleukin-36 alpha, FIL1 epsilon, Interleukin-1 epsilon, IL-1 epsilon, Interleukin-1 family member 6, IL-1F6, IL36A, FIL1E, IL1E, IL1F6

    Tissue Specificity: Expressed in immune system and fetal brain, but not in other tissues tested or in multiple hematopoietic cell lines. Predominantly expressed in skin keratinocytes but not in fibroblasts, endothelial cells or melanocytes. Increased in lesional psoriasis skin.

    Background: Ribosomal RNA-processing protein 8 is a protein that in humans is encoded by the RRP8 gene. Enables methylated histone binding activity. Involved in several processes, including cellular response to glucose starvation, intrinsic apoptotic signaling pathway by p53 class mediator, and regulation of gene expression. Located in several cellular components, including cytosol, nuclear lumen, and rDNA heterochromatin. Part of chromatin silencing complex.

    Molekulargewicht

    65 kDa

    Gen-ID

    23378

    UniProt

    O43159
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