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RRP8 Antikörper

RRP8 Reaktivität: Human, Ratte, Maus WB, ELISA, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7118623
  • Target Alle RRP8 Antikörper anzeigen
    RRP8 (Ribosomal RNA Processing 8 (RRP8))
    Reaktivität
    • 22
    • 10
    • 9
    • 4
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    Human, Ratte, Maus
    Wirt
    • 20
    • 2
    Kaninchen
    Klonalität
    • 22
    Polyklonal
    Konjugat
    • 15
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser RRP8 Antikörper ist unkonjugiert
    Applikation
    • 13
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
    Aufreinigung
    Immunogen affinity purified
    Reinheit
    ≥95 % as determined by SDS-PAGE
    Immunogen
    ribosomal RNA processing 8, methyltransferase, homolog(yeast)
    Isotyp
    IgG
    Top Product
    Discover our top product RRP8 Primärantikörper
  • Applikationshinweise
    WB: 1:500-1:2000, IHC: 1:20-1:200, IF: 1:20-1:200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
    Haltbarkeit
    12 months
  • Target
    RRP8 (Ribosomal RNA Processing 8 (RRP8))
    Andere Bezeichnung
    RRP8 (RRP8 Produkte)
    Synonyme
    KIAA0409 antikoerper, 1500003O22Rik antikoerper, 2900001K19Rik antikoerper, AW538116 antikoerper, RGD1308302 antikoerper, ribosomal RNA processing 8 antikoerper, ribosomal RNA processing 8, methyltransferase, homolog (yeast) antikoerper, RRP8 antikoerper, Rrp8 antikoerper
    Hintergrund
    Synonyms:KIAA0409, NML Background:Essential component of the eNoSC(energy-dependent nucleolar silencing) complex, a complex that mediates silencing of rDNA in response to intracellular energy status and acts by recruiting histone-modifying enzymes. The eNoSC complex is able to sense the energy status of cell: upon glucose starvation, elevation of NAD(+)/NADP(+) ratio activates SIRT1, leading to histone H3 deacetylation followed by dimethylation of H3 at 'Lys-9'(H3K9me2) by SUV39H1 and the formation of silent chromatin in the rDNA locus. In the complex, RRP8 binds to H3K9me2 and probably acts as a methyltransferase. Its substrates are however unknown.
    Molekulargewicht
    51 kDa
    Gen-ID
    23378
    UniProt
    O43159
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