FGF3 Antikörper (AA 18-239)

Produktnummer ABIN7600325

Dieses Anti-FGF3-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von FGF3 in IHC und ELISA. Geeignet für Human.

Kurzübersicht für FGF3 Antikörper (AA 18-239) (ABIN7600325)

Target: FGF3 (Fibroblast Growth Factor 3 (FGF3))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FGF3 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), ELISA

Produktdetails anti-FGF3 Antikörper

Bindungsspezifität: AA 18-239

Verwendungszweck: Anti-FGF3 Antibody

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Produktmerkmale: Anti-FGF3 Antibody Picoband® (ABIN7600325). Tested in ELISA, IHC applications. This antibody reacts with Human.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human FGF3 recombinant protein (Position: A18-H239).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human
ELISA, 0.1-0.5 μg/mL, -
1. Alsmadi, O., Meyer, B. F., Alkuraya, F, Wakil, S., Alkayal, F., Al-Saud, H., Ramzan, K., Al-Sayed, M. Syndromic congenital sensorineural deafness, microtia and microdontia resulting from a novel homoallelic mutation in fibroblast growth factor 3 (FGF3). Europ. J. Hum. Genet. 17: 14-21, 2009. 2. Brookes, S., Smith, R., Casey, G., Dickson, C., Peters, G. Sequence organization of the human int-2 gene and its expression in teratocarcinoma cells. Oncogene 4: 429-436, 1989. 3. Casey, G., Smith, R., McGillivray, D., Peters, G., Dickson, C. Characterization and chromosome assignment of the human homolog of int-2, a potential proto-oncogene. Molec. Cell. Biol. 6: 502-510, 1986.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Details zu FGF3

Target: FGF3 (Fibroblast Growth Factor 3 (FGF3))

Andere Bezeichnung: FGF3

Hintergrund:

Synonyms: Glutathione S-transferase Mu 3, GST class-mu 3, GSTM3-3, hGSTM3-3, GSTM3, GST5,

Tissue Specificity: Testis and brain.

Background: INT-2 proto-oncogene protein also known as FGF-3 is a protein that in humans is encoded by the FGF3 gene. The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This gene was identified by its similarity with mouse fgf3/int-2, a proto-oncogene activated in virally induced mammary tumors in the mouse. Frequent amplification of this gene has been found in human tumors, which may be important for neoplastic transformation and tumor progression. Studies of the similar genes in mouse and chicken suggested the role in inner ear formation.

Molekulargewicht: 33 kDa

Gen-ID: 2248

UniProt: P11487

Pathways: RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung