Peroxiredoxin 6 Antikörper (AA 15-224)

Produktnummer ABIN7600102

Dieses Anti-Peroxiredoxin 6-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von Peroxiredoxin 6 in WB, IHC, ICC, IF und FACS. Geeignet für Human, Maus und Ratte.

Kurzübersicht für Peroxiredoxin 6 Antikörper (AA 15-224) (ABIN7600102)

Target: Peroxiredoxin 6 (PRDX6)

Reaktivität: Human, Maus, Ratte

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Peroxiredoxin 6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF), Flow Cytometry (FACS)

Klon: 6I8

Produktdetails anti-Peroxiredoxin 6 Antikörper

Bindungsspezifität: AA 15-224

Verwendungszweck: Anti-PRDX6 Antibody Picoband® (monoclonal, 6I8)

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Produktmerkmale: Anti-PRDX6 Antibody Picoband® (monoclonal, 6I8) (ABIN7600102). Tested in Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human Peroxiredoxin 6 recombinant protein (Position: E15-P224). Human Peroxiredoxin 6 shares 90% and 91% amino acid (aa) sequence identity with mouse and rat Peroxiredoxin 6, respectively.

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise: Western blot, 0.25-0.5 μg/mL, Human, Rat
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 2 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
1. Ambruso DR, et al. Peroxiredoxin 6 translocates to the plasma membrane during neutrophil activation and is required for optimal NADPH oxidase activity. Biochim Biophys Acta, 2012 Feb. 2. Chhunchha B, et al. Aberrant sumoylation signaling evoked by reactive oxygen species impairs protective function of Prdx6 by destabilization and repression of its transcription. FEBS J, 2014 Aug. 3. Guo HW, et al. Expression of peroxiredoxin 6 in gastric cancer and its clinical significance. Zhonghua Yi Xue Za Zhi, 2012 Sep 11.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Details zu Peroxiredoxin 6

Target: Peroxiredoxin 6 (PRDX6)

Andere Bezeichnung: PRDX6

Hintergrund:

Synonyms: Peroxiredoxin-6,1.11.1.15,1-Cys peroxiredoxin,1-Cys PRX,24 kDa protein,Acidic calcium-independent phospholipase A2,aiPLA2,3.1.1.-,Antioxidant protein 2,Liver 2D page spot 40,Non-selenium glutathione peroxidase,NSGPx,1.11.1.9,Red blood cells page spot 12,PRDX6,AOP2, KIAA0106,

Tissue Specificity: Widely expressed in fetal and adult tissues.

Background: PRDX6 is also known as PRX, p29 or AOP2. The protein encoded by this gene is a member of the thiol-specific antioxidant protein family. This protein is a bifunctional enzyme with two distinct active sites. It is involved in redox regulation of the cell, it can reduce H (2)O (2) and short chain organic, fatty acid, and phospholipid hydroperoxides. It may play a role in the regulation of phospholipid turnover as well as in protection against oxidative injury.

Molekulargewicht: 29 kDa.

Gen-ID: 9588

UniProt: P30041