EDEM1 Antikörper (AA 124-657)
Kurzübersicht für EDEM1 Antikörper (AA 124-657) (ABIN7599876)
Target
Alle EDEM1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 124-657
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Verwendungszweck
- Anti-EDEM1 Antibody
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Kreuzreaktivität (Details)
- No cross-reactivity with other proteins
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Homologie
- Human EDEM1 shares 96.6% amino acid (aa) sequence identity with mouse EDEM1.
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Produktmerkmale
- Anti-EDEM1 Antibody. Tested in WB, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse, Rat.
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Aufreinigung
- Immunogen affinity purified.
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Immunogen
- E.coli-derived human EDEM1 recombinant protein (Position: P124-I657). Human EDEM1 shares 96.6% amino acid (aa) sequence identity with mouse EDEM1.
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Isotyp
- IgG
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Applikationshinweise
- Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human ELISA, 0.1-0.5 μg/mL
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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Konzentration
- 500 μg/mL
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Buffer
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing. -
Haltbarkeit
- 12 months
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- EDEM1 (ER Degradation Enhancer, Mannosidase alpha-Like 1 (EDEM1))
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Andere Bezeichnung
- EDEM1
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Hintergrund
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Background: Enables mannosyl-oligosaccharide 1,2-alpha-mannosidase activity and misfolded protein binding activity. Involved in positive regulation of retrograde protein transport, ER to cytosol, protein targeting to ER, and proteolysis involved in protein catabolic process. Located in aggresome and endoplasmic reticulum quality control compartment.
Gene Full Name: ER degradation enhancing alpha-mannosidase like protein 1
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Molekulargewicht
- 66 kDa
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Gen-ID
- 9695
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UniProt
- Q92611
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Pathways
- ER-Nucleus Signaling
Target
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