EDEM1 Antikörper (AA 46-128)

Produktnummer ABIN7151970

Produktdetails anti-EDEM1 Antikörper

Target: EDEM1 (ER Degradation Enhancer, Mannosidase alpha-Like 1 (EDEM1))

Bindungsspezifität: AA 46-128

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser EDEM1 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC)

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human ER degradation-enhancing alpha-mannosidase-like protein 1 protein (46-128AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: IHC:1:200-1:500,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu EDEM1

Target: EDEM1 (ER Degradation Enhancer, Mannosidase alpha-Like 1 (EDEM1))

Andere Bezeichnung: EDEM1 (EDEM1 Produkte)

Synonyme: zgc:55816 antikoerper, edem antikoerper, EDEM1 antikoerper, EDEM antikoerper, A130059K23Rik antikoerper, mKIAA0212 antikoerper, RGD1563633 antikoerper, ER degradation enhancer, mannosidase alpha-like 1 antikoerper, ER degradation enhancing alpha-mannosidase like protein 1 antikoerper, ER degradation-enhancing alpha-mannosidase-like protein 1 antikoerper, ER degradation enhancing alpha-mannosidase like protein 1 L homeolog antikoerper, edem1 antikoerper, EDEM1 antikoerper, LOC100637820 antikoerper, edem1.L antikoerper, Edem1 antikoerper

Hintergrund:

Background: Extracts misfolded glycoproteins, but not glycoproteins undergoing productive folding, from the calnexin cycle. It is directly involved in endoplasmic reticulum-associated degradation (ERAD) and targets misfolded glycoproteins for degradation in an N-glycan-independent manner, probably by forming a complex with SEL1L. It has low mannosidase activity, catalyzing mannose trimming from Man8GlcNAc2 to Man7GlcNAc2.

Aliases: EDEM1 antibody, EDEM antibody, KIAA0212ER degradation-enhancing alpha-mannosidase-like protein 1 antibody

UniProt: Q92611

Pathways: ER-Nucleus Signaling