Angiomotin Antikörper (AA 12-622)
Kurzübersicht für Angiomotin Antikörper (AA 12-622) (ABIN7599826)
Target
Alle Angiomotin (AMOT) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 12-622
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Verwendungszweck
- Anti-Angiomotin/AMOT Antibody
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Kreuzreaktivität (Details)
- No cross-reactivity with other proteins.
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Produktmerkmale
- Anti-Angiomotin/AMOT Antibody (ABIN7599826). Tested in ELISA, Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.
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Aufreinigung
- Immunogen affinity purified.
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Immunogen
- E.coli-derived human Angiomotin/AMOT recombinant protein (Position: T12-Q622).
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Isotyp
- IgG
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Applikationshinweise
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Western blot, 0.25-0.5 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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Konzentration
- 500 μg/mL
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Buffer
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- Angiomotin (AMOT)
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Andere Bezeichnung
- AMOT
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Hintergrund
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Synonyms: Endothelial cell-specific molecule 1, ESM-1, ESM1
Tissue Specificity: Expressed in lung, on the vascular capillary network within alveolar walls, and also at lower level in kidney.
Background: Angiomotin (AMOT) is a protein that in humans is encoded by the AMOT gene. This gene belongs to the motin family of angiostatin binding proteins characterized by conserved coiled-coil domains and C-terminal PDZ binding motifs. The encoded protein is expressed predominantly in endothelial cells of capillaries as well as larger vessels of the placenta where it may mediate the inhibitory effect of angiostatin on tube formation and the migration of endothelial cells toward growth factors during the formation of new blood vessels. Alternative splicing results in multiple transcript variants encoding different isoforms.
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Molekulargewicht
- 140 kDa
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Gen-ID
- 154796
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Pathways
- Cell-Cell Junction Organization, Regulation of Cell Size
Target
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