Angiomotin Antikörper (AA 285-312)

Produktnummer ABIN6242716

Der Kaninchen Polyklonal anti-Angiomotin Antikörper (Klon RB40425) (ABIN6242716) detektiert spezifisch Angiomotin in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für Angiomotin Antikörper (AA 285-312) (ABIN6242716)

Target: Angiomotin (AMOT)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Angiomotin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: RB40425

Produktdetails anti-Angiomotin Antikörper

Bindungsspezifität: AA 285-312

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This AMOT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 285-312 amino acids from the Central region of human AMOT.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Details zu Angiomotin

Target: Angiomotin (AMOT)

Andere Bezeichnung: AMOT

Hintergrund: This gene belongs to the motin family of angiostatin binding proteins characterized by conserved coiled-coil domains and C-terminal PDZ binding motifs. The encoded protein is expressed predominantly in endothelial cells of capillaries as well as larger vessels of the placenta where it may mediate the inhibitory effect of angiostatin on tube formation and the migration of endothelial cells toward growth factors during the formation of new blood vessels. Alternative splicing results in multiple transcript variants encoding different isoforms.

Molekulargewicht: 118085

NCBI Accession: NP_001106962, NP_573572

UniProt: Q4VCS5

Pathways: Cell-Cell Junction Organization, Regulation of Cell Size