RAD51C Antikörper (AA 11-342)

Produktnummer ABIN7599718

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch RAD51C in WB, ELISA, IHC und FACS. Er zeigt eine Reaktivität gegenüber Human und Ratte.

Kurzübersicht für RAD51C Antikörper (AA 11-342) (ABIN7599718)

Target: RAD51C (DNA Repair Protein RAD51 Homolog 3 (RAD51C))

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RAD51C Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)

Produktdetails anti-RAD51C Antikörper

Bindungsspezifität: AA 11-342

Verwendungszweck: Anti-RAD51C Antibody Picoband®

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Produktmerkmale: Anti-RAD51C Antibody Picoband® (ABIN7599718). Tested in ELISA, Flow Cytometry, IHC, WB applications. This antibody reacts with Human, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human RAD51C recombinant protein (Position: Q11-K342).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.25-0.5 μg/mL, Human, Rat
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. "Entrez Gene: RAD51C RAD51 homolog C (S. cerevisiae)". 2. Dosanjh MK, Collins DW, Fan W, Lennon GG, Albala JS, Shen Z, Schild D (March 1998). "Isolation and characterization of RAD51C, a new human member of the RAD51 family of related genes". Nucleic Acids Res. 26 (5): 1179-84.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Details zu RAD51C

Target: RAD51C (DNA Repair Protein RAD51 Homolog 3 (RAD51C))

Andere Bezeichnung: RAD51C

Hintergrund:

Synonyms: Period circadian protein homolog 3, hPER3, Cell growth-inhibiting gene 13 protein, Circadian clock protein PERIOD 3, PER3, GIG13

Background: RAD51 homolog C (S. cerevisiae), also known as RAD51C, is a protein which in humans is encoded by the RAD51C gene. This gene is a member of the RAD51 family of related genes, which encode strand-transfer proteins thought to be involved in recombinational repair of damaged DNA and in meiotic recombination. Ana this gene product interacts with two other DNA repair proteins, encoded by RAD51B and XRCC3, but not with itself. The protein copurifies with XRCC3 protein in a complex, reflecting their endogenous association and suggesting a cooperative role during recombinational repair. This gene is one of four localized to a region of chromosome 17q23 where amplification occurs frequently in breast tumors. Overexpression of the four genes during amplification has been observed and suggests a possible role in tumor progression. Alternative splicing has been observed for this gene and two variants encoding different isoforms have been identified.

Molekulargewicht: 42 kDa

Gen-ID: 5889

UniProt: O43502

Pathways: DNA Reparatur