GLS2 Antikörper (AA 1-602)

Produktnummer ABIN7599493

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch GLS2 in WB, ELISA und FACS. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für GLS2 Antikörper (AA 1-602) (ABIN7599493)

Target: GLS2 (Glutaminase 2 (Liver, Mitochondrial) (GLS2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GLS2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Produktdetails anti-GLS2 Antikörper

Bindungsspezifität: AA 1-602

Verwendungszweck: Anti-GLS2 Antibody Picoband®

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Produktmerkmale: Anti-GLS2 Antibody Picoband® (ABIN7599493). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human GLS2 recombinant protein (Position: M1-V602).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.25-0.5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Gomez-Fabre, P. M., Aledo, J. C., del Castillo-Olivares, A., Alonso, F. J., Nunez de Castro, I., Campos, J. A., Marquez, J. Molecular cloning, sequencing and expression studies of the human breast cancer cell glutaminase. Biochem. J. 345: 365-375, 2000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Details zu GLS2

Target: GLS2 (Glutaminase 2 (Liver, Mitochondrial) (GLS2))

Andere Bezeichnung: GLS2

Hintergrund:

Synonyms: Cytoskeleton-associated protein 5, Colonic and hepatic tumor overexpressed gene protein, Ch-TOG, CKAP5, KIAA0097

Tissue Specificity: Expressed in fetal brain. Highly expressed in brain and placenta. Lower levels in heart, liver, thymus, kidney and lung. Located to endothelial cells and neuronal cells of the suprachiasmatic nucleus (SCN). Also detected in endothelial cells of the heart, lung and kidney. In the brain, specifically expressed in the thalamus, hippocampus and amygdala.

Background: Glutaminase 2 (liver, mitochondrial) is a protein that in humans is encoded by the GLS2 gene. The protein encoded by this gene is a mitochondrial phosphate-activated glutaminase that catalyzes the hydrolysis of glutamine to stoichiometric amounts of glutamate and ammonia. Originally thought to be liver-specific, this protein has been found in other tissues as well. Alternative splicing results in multiple transcript variants that encode different isoforms.

Molekulargewicht: 66 kDa

Gen-ID: 27165

Pathways: Dicarboxylic Acid Transport, Warburg Effekt