Glutaminase 2 (Liver, Mitochondrial) (GLS2) (Middle Region) Antikörper

Details zu Produkt Nr. ABIN2781319
Antigen
  • si:ch211-216k22.10
  • GA
  • GLS
  • LGA
  • hLGA
  • A330074B06Rik
  • AI195532
  • Lga
  • Ga
  • glutaminase 2
  • glutaminase 2a (liver, mitochondrial)
  • glutaminase 2 (liver, mitochondrial)
  • glsA2
  • LOAG_03311
  • gls2a
  • GLS2
  • Gls2
Epitop
Middle Region
9
9
7
7
4
3
2
1
1
1
1
Reaktivität
Rind (Kuh), Hund, Meerschweinchen, Pferd, Human, Maus, Schwein, Kaninchen, Ratte (Rattus), Zebrafisch (Danio rerio)
53
35
24
1
1
1
1
1
Wirt
Kaninchen
52
2
Klonalität
Polyklonal
Konjugat
Unkonjugiert
4
4
4
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Applikation
Immunohistochemistry (IHC), Western Blotting (WB)
37
28
25
13
5
2
1
1
Optionen
Immunogen The immunogen is a synthetic peptide directed towards the middle region of human GLS2
Sequenz FVGKEPSGLR YNKLSLNEEG IPHNPMVNAG AIVVSSLIKM DCNKAEKFDF
Homologie Cow: 93%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 79%
Produktmerkmale This is a rabbit polyclonal antibody against GLS2. It was validated on Western Blot and immunohistochemistry.
Reinigung Protein A purified
Antigen
Andere Bezeichnung GLS2 (GLS2 Antibody Abstract)
Hintergrund GLS2 is a mitochondrial phosphate-activated glutaminase that catalyzes the hydrolysis of glutamine to stoichiometric amounts of glutamate and ammonia. This protein is functionally similar to the kidney glutaminase but is a little smaller in size. Originally thought to be liver-specific, this protein has been found in other tissues as well.
Alias Symbols: GA, GLS, LGA, MGC71567, hLGA
Protein Interaction Partner: SNTA1, GRHPR, TAX1BP3, PAG1, DLG2, INADL, DLG4, RGS3, DLG1, DLG3, CASK,
Protein Size: 327
Molekulargewicht 36 kDa
Gen-ID 27165
NCBI Accession NM_013267
UniProt Q9UI32
Pathways Dicarboxylic Acid Transport
Applikations-hinweise Optimal working dilutions should be determined experimentally by the investigator.
Kommentare

Antigen size: 327 AA

Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid repeated freeze-thaw cycles.
Lagerung -20 °C
Informationen zur Lagerung For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Bilder des Herstellers
Immunohistochemistry (IHC) image for anti-Glutaminase 2 (Liver, Mitochondrial) (GLS2) (Middle Region) antibody (ABIN2781319) anti-Glutaminase 2 (Liver, Mitochondrial) (GLS2) (Middle Region) antibody
Western Blotting (WB) image for anti-Glutaminase 2 (Liver, Mitochondrial) (GLS2) (Middle Region) antibody (ABIN2781319) WB Suggested Antibody Titration: 2.5ug/ml Positive Control: HepG2 GLS2 is supporte...
Immunohistochemistry (IHC) image for anti-Glutaminase 2 (Liver, Mitochondrial) (GLS2) (Middle Region) antibody (ABIN2781319) Human kidney
Western Blotting (WB) image for anti-Glutaminase 2 (Liver, Mitochondrial) (GLS2) (Middle Region) antibody (ABIN2781319) Host: Rabbit Target Name: GLS2 Sample Tissue: Human NCI-H226 Antibody Dilution:...
Produkt verwendet in: Hu, Lausted, Yoo, Yan, Brightman, Chen, Wang, Bu, Hood: "Quantitative liver-specific protein fingerprint in blood: a signature for hepatotoxicity." in: Theranostics, Vol. 4, Issue 2, pp. 215-28, 2014 (PubMed).

Toriumi, Mouri, Narusawa, Aoyama, Ikawa, Lu, Nagai, Mamiya, Kim, Nabeshima: "Prenatal NMDA receptor antagonism impaired proliferation of neuronal progenitor, leading to fewer glutamatergic neurons in the prefrontal cortex." in: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, Vol. 37, Issue 6, pp. 1387-96, 2012 (PubMed).

Haben Sie etwas anderes gesucht?