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PIK3R6 Antikörper (AA 1-537)

Der Kaninchen Polyklonal Anti-PIK3R6-Antikörper wurde für WB, ELISA und FACS validiert. Er ist geeignet, PIK3R6 in Proben von Human zu detektieren.
Produktnummer ABIN7599470

Kurzübersicht für PIK3R6 Antikörper (AA 1-537) (ABIN7599470)

Target

Alle PIK3R6 Antikörper anzeigen
PIK3R6 (Phosphoinositide-3-Kinase, Regulatory Subunit 6 (PIK3R6))

Reaktivität

  • 13
  • 1
  • 1
  • 1
  • 1
  • 1
Human

Wirt

  • 9
  • 4
Kaninchen

Klonalität

  • 10
  • 3
Polyklonal

Konjugat

  • 10
  • 1
  • 1
  • 1
Dieser PIK3R6 Antikörper ist unkonjugiert

Applikation

  • 10
  • 8
  • 5
  • 4
  • 1
  • 1
Western Blotting (WB), ELISA, Flow Cytometry (FACS)
  • Bindungsspezifität

    • 5
    • 5
    • 3
    • 2
    • 1
    • 1
    AA 1-537

    Verwendungszweck

    Anti-PIK3R6 Antibody Picoband®

    Kreuzreaktivität (Details)

    No cross-reactivity with other proteins

    Produktmerkmale

    Anti-PIK3R6 Antibody Picoband® (ABIN7599470). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    Aufreinigung

    Immunogen affinity purified.

    Immunogen

    E.coli-derived human PIK3R6 recombinant protein (Position: M1-Q537).

    Isotyp

    IgG
  • Applikationshinweise

    Western blot, 0.25-0.5 μg/mL, Human
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
    ELISA, 0.1-0.5 μg/mL, -
    1. Voigt, P., Dorner, M. B., Schaefer, M. Characterization of p87-PIKAP, a novel regulatory subunit of phosphoinositide 3 kinase-gamma that is highly expressed in heart and interacts with PDE3B. J. Biol. Chem. 281: 9977-9986, 2006.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    Konzentration

    500 μg/mL

    Buffer

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • Target

    PIK3R6 (Phosphoinositide-3-Kinase, Regulatory Subunit 6 (PIK3R6))

    Andere Bezeichnung

    PIK3R6

    Hintergrund

    Synonyms: RNA-binding protein 47,RNA-binding motif protein 47,RBM47,

    Tissue Specificity: Abundantly expressed in tonsil, lymph node, and trachea, strong expression in prostate, lower expression in thyroid, stomach, and colon. .

    Background: Phosphoinositide 3-kinase gamma is a lipid kinase that produces the lipid second messenger phosphatidylinositol 3,4,5-trisphosphate. The kinase is composed of a catalytic subunit and one of several regulatory subunits, and is chiefly activated by G protein-coupled receptors. This gene encodes a regulatory subunit, and is distantly related to the phosphoinositide-3-kinase, regulatory subunit 5 gene which is located adjacent to this gene on chromosome 7. The orthologous protein in the mouse binds to both the catalytic subunit and to G(beta/gamma), and mediates activation of the kinase subunit downstream of G protein-coupled receptors. Alternative splicing results in multiple transcript variants.

    Molekulargewicht

    84 kDa

    Gen-ID

    146850

    Pathways

    PI3K-Akt Signalweg, Inositol Metabolic Process
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