Exonuclease 1 Antikörper (AA 1-294)

Produktnummer ABIN7599229

Dieser Kaninchen Polyklonal Antikörper erkennt spezifisch Exonuclease 1 in WB, ELISA, IHC und FACS. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für Exonuclease 1 Antikörper (AA 1-294) (ABIN7599229)

Target: Exonuclease 1 (EXO1)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Exonuclease 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)

Produktdetails anti-Exonuclease 1 Antikörper

Bindungsspezifität: AA 1-294

Verwendungszweck: Anti-Exonuclease 1/EXO1 Antibody

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Produktmerkmale: Anti-Exonuclease 1/EXO1 Antibody (ABIN7599229). Tested in ELISA, Flow Cytometry, IHC, WB applications. This antibody reacts with Human. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human Exonuclease 1/EXO1 recombinant protein (Position: M1-K294).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.25-0.5 μg/mL, Human
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Details zu Exonuclease 1

Target: Exonuclease 1 (EXO1)

Andere Bezeichnung: EXO1

Hintergrund:

Synonyms: Exodeoxyribonuclease 1, Exodeoxyribonuclease I, EXO I, Exonuclease I, Protein DHS1, EXO1, DHS1, YOR033C, OR26.23

Tissue Specificity: Highly expressed in bone marrow, testis and thymus. Expressed at lower levels in colon, lymph nodes, ovary, placenta, prostate, small intestine, spleen and stomach.

Background: Exonuclease 1?is an?enzyme?that in humans is encoded by the?EXO1?gene. It is mapped to 1q43. This gene encodes a protein with 5' to 3' exonuclease activity as well as an RNase H activity. It is similar to the Saccharomyces cerevisiae protein Exo1 which interacts with Msh2 and which is involved in mismatch repair and recombination. Alternative splicing of this gene results in three transcript variants encoding two different isoforms.

Molekulargewicht: 120 kDa

Gen-ID: 9156

Pathways: DNA Reparatur, Production of Molecular Mediator of Immune Response