Leptin Antikörper (AA 22-167)

Produktnummer ABIN7596041

Dieses Anti-Leptin-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von Leptin in WB, ELISA, ICC und IF. Geeignet für Human.

Kurzübersicht für Leptin Antikörper (AA 22-167) (ABIN7596041)

Target: Leptin (LEP)

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Leptin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)

Klon: AT7E10

Produktdetails anti-Leptin Antikörper

Bindungsspezifität: AA 22-167

Verwendungszweck: Human Leptin/OB antibody

Aufreinigung: protein-A affinity chromatography

Immunogen: Recombinant human Leptin/OB (22-167aa) purified from E. coli.

Isotyp: IgG2b kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% glycero

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.

Details zu Leptin

Target: Leptin (LEP)

Andere Bezeichnung: Leptin/OB

Hintergrund: Human leptin is a 16- kDa nonglycosylated hormone that is produced in mature adipocytes. Leptin acts primarilyin the hypothalamus to reduce food intake and body weight. In ob/ob mice, the gene encoding leptin is mutated,resulting in morbid obesity and associated abnormalities, including hyperphagia, hypothermia, diabetes andinfertility. The function of leptin in regulating appetite and metabolism, as well as the possibility of usingleptin as a therapeutic agent, are currently under intense investigation.

NCBI Accession: NP_000221

Pathways: JAK-STAT Signalweg, AMPK Signaling, Hormone Transport, Peptide Hormone Metabolism, Hormone Activity, Negative Regulation of Hormone Secretion, Regulation of Carbohydrate Metabolic Process, Feeding Behaviour, Monocarboxylic Acid Catabolic Process