PINK1 Antikörper (AA 112-496)

Produktnummer ABIN7595933

Dieses Maus Monoklonal-Antikörper erkennt spezifisch PINK1 in WB, IHC und ICC. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für PINK1 Antikörper (AA 112-496) (ABIN7595933)

Target: PINK1 (PTEN Induced Putative Kinase 1 (PINK1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser PINK1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC)

Klon: N4-49

Produktdetails anti-PINK1 Antikörper

Bindungsspezifität: AA 112-496

Verwendungszweck: Anti-Pink1 PTEN Induced Putative Kinase 1 Antibody

Spezifität: No off-targets reported

Kreuzreaktivität: Human

Produktmerkmale:

Description: Our Anti-Pink1 PTEN induced putative kinase 1 mouse monoclonal primary antibody is produced in-house from hybridoma clone N4/49. It detects human Pink1 PTEN induced putative kinase 1, and is purified by Protein A chromatography. It is great for use in IHC, ICC, WB.

Manufacturer Comment: We produce our Pink1 PTEN induced putative kinase 1 mouse monoclonal primary antibody from hybridoma clone N4/49. It is great in IHC, ICC, WB and is purified by Protein A chromatography.

Aufreinigung: Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography.

Reinheit: > 90 % specific antibody

Immunogen: Fusion protein amino acids 112-496 of human Pink1 (accession number NP_115785) produced recombinantly in E. Coli

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 10 mM Tris, 50 mM Sodium Chloride, 0.065 % Sodium Azide pH 7.4

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Haltbarkeit: 24 months

Details zu PINK1

Target: PINK1 (PTEN Induced Putative Kinase 1 (PINK1))

Andere Bezeichnung: Pink1 PTEN induced putative kinase 1

Hintergrund:

Synonyms: Serine/threonine-protein kinase PINK1, mitochondrial (EC 2.7.11.1) (BRPK) (PTEN-induced putative kinase protein 1)

Target Description: PTEN Induced Kinase 1 is encoded by the gene PINK1. PINK1 is a member of the protein kinase superfamily, Ser/Thr protein kinase family. PINK1 is a serine/threonine protein kinase that protects against mitochondrial dysfunction during cellular stress by phosphorylating mitochondrial proteins. PINK1 is highly expressed in the heart, skeletal muscle, and testis. Diseases associated with PINK1 include Parkinson Disease 6, Autosomal Recessive Early-Onset and Parkinson Disease 2, Autosomal Recessive Juvenile.

Gene Name Alternatives: PINK1

Molekulargewicht: 63 kDa

Pathways: Autophagie