PD-1 Antikörper (Elab Fluor®700)

Produktnummer ABIN7566875

Der Ratte Monoklonal Anti-PD-1-Antikörper wurde für FACS validiert. Er ist geeignet, PD-1 in Proben von Maus zu detektieren.

Kurzübersicht für PD-1 Antikörper (Elab Fluor®700) (ABIN7566875)

Target: PD-1 (PDCD1) (Programmed Cell Death 1 (PDCD1))

Reaktivität: Maus

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser PD-1 Antikörper ist konjugiert mit Elab Fluor®700

Applikation: Flow Cytometry (FACS)

Klon: 29F-1A12

Produktdetails anti-PD-1 Antikörper (Elab Fluor®700)

Verwendungszweck: Elab Fluor®700 Anti-Mouse CD279/PD-1 Antibody[29F.1A12]

Isotyp: IgG2a, kappa

Anwendungsinformationen

Applikationshinweise: Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/10 cells in 100 μL volume].

Kommentare:

Matching Isotype Control: E-AB-F09833M1

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Phosphate buffered solution, pH 7.2, containing 0.09 % stabilizer and 1 % protein protectant.

Lagerung: 4 °C

Informationen zur Lagerung: This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.

Haltbarkeit: 12 months

Details zu PD-1

Target: PD-1 (PDCD1) (Programmed Cell Death 1 (PDCD1))

Andere Bezeichnung: CD279/PD-1

Hintergrund: Programmed Death-1,PD-1,CD279, also known as programmed death-1 (PD-1), is a 50-55 kD glycoprotein belonging to the CD28 family of the Ig superfamily. PD-1 is expressed on activated splenic T and B cells and thymocytes. It is induced on activated myeloid cells as well. PD-1 is involved in lymphocyte clonal selection and peripheral tolerance through binding its ligands, B7-H1 (PD-L1) and B7-DC (PD-L2). It has been reported that PD-1 and PD-L1 interactions are critical to positive selection and play a role in shaping the T cell repertoire. PD-L1 negative costimulation is essential for prolonged survival of intratesticular islet allografts.

Gen-ID: 18566

UniProt: Q02242

Pathways: Cancer Immune Checkpoints